SCHEMBL4409512

SCHEMBL4409512

NNC(=O)COc1ccc(Cc2ccc(OCC(=O)NN)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
KDM4E B2RXH2 3/20 0.56
LMNA P02545 3/20 0.56
OGG1 O15527 1/20 0.50
MAPT P10636 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
FAAH O00519 1/20 0.46
ACHE P22303 1/20 0.46
MAPK1 P28482 1/20 0.45
CASP3 P42574 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4422333 0.90 ALDH1A1 (0.73) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL15426830 0.85 ALDH1A1 (0.68) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL4413701 0.85 ALDH1A1 (0.67) ALDH1A1KDM4ELMNAOGG1MAPT
SCHEMBL5804184 0.84 ALDH1A1 (0.58) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL4419519 0.82 LTA4H (0.50) KDM4E
SCHEMBL2835832 0.81 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL1713424 0.81 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAMAPTMEN1
SCHEMBL11547674 0.81 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL1303739 0.81 ALDH1A1 (0.68) ALDH1A1KDM4ELMNAOGG1MAPT
SCHEMBL5434584 0.81 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2684907-B1 RESIN, OPTICAL MATERIAL, AND OPTICAL DEVICE MITSUI CHEMICALS INC (JP) 2020-02-26 EP disclosed
US-9221949-B2 Resin, optical material, and optical device MITSUI CHEMICALS, INC. (JP) 2015-12-29 US disclosed
EP-2684907-A1 RESIN, OPTICAL MATERIAL, AND OPTICAL DEVICE Mitsui Chemicals, Inc. (JP) 2014-01-15 EP disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed