Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 3/20 | 0.66 |
| ▸ | CDK1 | P06493 | 3/20 | 0.66 |
| ▸ | CDK4 | P11802 | 3/20 | 0.66 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.66 |
| ▸ | CCND1 | P24385 | 3/20 | 0.66 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 8/20 | 0.44 |
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035424 | 0.83 | CCNB2 (0.66) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9035429 | 0.83 | CCNB2 (0.66) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4683688 | 0.83 | CCNB2 (0.65) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4683690 | 0.83 | CCNB2 (0.65) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL2871692 | 0.82 | MAOA (0.62) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8709017 | 0.81 | CCNB2 (0.62) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8709013 | 0.81 | CCNB2 (0.62) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL6339806 | 0.81 | CCNB2 (0.62) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL6339803 | 0.81 | CCNB2 (0.62) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL18587010 | 0.80 | CCNB2 (0.61) | CCNB2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324750-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF PSEUDOLYSIMACHION LONGIFOLIUM AND THE CATALPOL DERIVATIVES ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-12-31 | — | — | US | claimed |
| CN-1279053-C | Modulators for beta-amyloid peptide aggregation comprising D-amino acids | PRAECIS PHARM INC (US) | 2006-10-11 | — | — | CN | disclosed |
| CN-1362967-A | D-amino acid-containing regulator of beta-amyloid peptide aggregation | PRAECIS PHARM INC (US) | 2002-08-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324750-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF PSEUDOLYSIMACHION LONGIFOLIUM AND THE CATALPOL DERIVATIVES ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY | IL4, IL5, MMP13 | CCNB2 4613/4885CDK1 4236/4885CDK4 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.