Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 3/20 | 0.65 |
| ▸ | CDK1 | P06493 | 3/20 | 0.65 |
| ▸ | CDK4 | P11802 | 3/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.65 |
| ▸ | CCND1 | P24385 | 3/20 | 0.65 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683688 | 1.00 | CCNB2 (0.65) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL14501310 | 0.84 | CYSLTR2 (0.59) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL353914 | 0.84 | MAOA (0.61) | LMNAACMSDALOX15PTPN7PPARG | |
| SCHEMBL4414016 | 0.83 | CCNB2 (0.66) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL3175679 | 0.82 | LMNA (0.54) | LMNAACMSDALOX15PTPN7ALDH1A1 | |
| SCHEMBL3175689 | 0.82 | LMNA (0.54) | LMNAACMSDALOX15PTPN7ALDH1A1 | |
| SCHEMBL4680821 | 0.81 | ALOX15 (0.53) | LMNAALOX15PTPN7ALDH1A1KDM4E | |
| SCHEMBL4680827 | 0.81 | ALOX15 (0.53) | LMNAALOX15PTPN7ALDH1A1KDM4E | |
| SCHEMBL3165146 | 0.81 | LMNA (0.53) | LMNAACMSDALOX15PTPN7ALDH1A1 | |
| SCHEMBL9813016 | 0.81 | LMNA (0.53) | LMNAACMSDALOX15PTPN7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386913-B1 | PYRROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-7220773-B2 | Heterocylic amines used as antidiabetic or hyperglycemic agents | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-20040162331-A1 | Pyrrole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-08-19 | — | — | US | disclosed |
| EP-1386913-A1 | PYRROLE DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162331-A1 | Pyrrole derivative | SLC5A1, GLP1R, SLC5A2 | CCNB2 4183/4885CDK1 3409/4885CDK4 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.