Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893710 | 0.85 | CYP1B1 (0.61) | MAPTALDH1A1HPGDCYP3A4CYP1B1 | |
| SCHEMBL5753797 | 0.81 | MAPT (1.00) | MAPTALDH1A1HPGDCYP3A4CYP1B1 | |
| SCHEMBL6200952 | 0.81 | MAPT (1.00) | MAPTALDH1A1HPGDCYP3A4CYP1B1 | |
| SCHEMBL76030 | 0.81 | MAPT (1.00) | MAPTALDH1A1HPGDCYP3A4CYP1B1 | |
| SCHEMBL7448677 | 0.80 | TNFRSF1A (0.53) | MAPTALDH1A1HPGDCYP3A4CYP1B1 | |
| SCHEMBL15112053 | 0.79 | SMN1; SMN2 (0.54) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL27977352 | 0.77 | MAPT (0.90) | MAPTALDH1A1HPGDCYP3A4CYP1B1 | |
| SCHEMBL31353024 | 0.77 | MAPT (0.78) | MAPTALDH1A1HPGDCYP3A4CYP1B1 | |
| SCHEMBL3954268 | 0.76 | CYP2A6 (0.50) | MAPTALDH1A1HPGDCYP3A4CYP1B1 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL18050340 | 0.76 | MAPT (0.68) | MAPTALDH1A1HPGDCYP3A4CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131589-A1 | CONTROLLED MOLECULAR WEIGHT AMINO ACID POLYMERS HAVING FUNCTIONALIZABLE BACKBONES AND END GROUPS AND PROCESSES FOR PREPARING THE SAME | UNIVERSITY OF ALABAMA IN HUNTSVILLE | 2009-05-21 | — | — | US | claimed |
| US-20090131589-A1 | CONTROLLED MOLECULAR WEIGHT AMINO ACID POLYMERS HAVING FUNCTIONALIZABLE BACKBONES AND END GROUPS AND PROCESSES FOR PREPARING THE SAME | UNIVERSITY OF ALABAMA IN HUNTSVILLE | 2009-05-21 | — | — | US | disclosed |
| WO-2009058291-A2 | CONTROLLED MOLECULAR WEIGHT AMINO ACID POLYMERS HAVING FUNCTIONALIZABLE BACKBONES AND END GROUPS AND PROCESSES FOR PREPARING THE SAME | UNIVERSITY OF ALABAMA IN HUNTSVILLE (US) | 2009-05-07 | — | — | WO | disclosed |