Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419437 | 0.84 | F10 (0.47) | F10SMN1; SMN2KDM4ESAE1UBA2 | |
| SCHEMBL4417487 | 0.82 | F10 (0.49) | F10 | |
| SCHEMBL4415800 | 0.81 | ALDH1A1 (0.49) | F10RAB9AALDH1A1NPC1MAPT | |
| SCHEMBL3373371 | 0.80 | F10 (0.56) | F10SMN1; SMN2KDM4EKDRALDH1A1 | |
| SCHEMBL4419134 | 0.79 | FLT3 (0.42) | F10SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL1382719 | 0.74 | F10 (0.75) | F10SMN1; SMN2KDM4EKDRALDH1A1 | |
| SCHEMBL4414253 | 0.71 | SMN1; SMN2 (0.53) | F10SMN1; SMN2TP53POLBRAB9A | |
| SCHEMBL3369686 | 0.67 | F10 (0.76) | F10SMN1; SMN2KDM4EKDRALDH1A1 | |
| SCHEMBL3369053 | 0.67 | F10 (0.57) | F10SMN1; SMN2KDM4EKDRALDH1A1 | |
| SCHEMBL3372771 | 0.66 | F10 (0.51) | F10SMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628972-B1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-22 | — | — | EP | claimed |