Diphenylmethane

Diphenylmethane

SCHEMBL4414601

CC(CC(=O)NN)NC(C)CC(=O)NN.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
PLA2G10 O15496 1/20 0.42
PLA2G2A P14555 1/20 0.42
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 3/20 0.41
TAAR1 Q96RJ0 2/20 0.41
MEN1 O00255 2/20 0.41
SLC18A2 Q05940 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL4421222 0.85 SLC1A3 (0.50) SLC1A3SLC1A2SLC1A1NPC1RAB9A
SCHEMBL4421218 0.77 SLC1A3 (0.42) SLC1A3SLC1A2SLC1A1NPC1RAB9A
Diphenylmethane SCHEMBL3685483 0.74 PLA2G10 (0.57) SLC1A3SLC1A2SLC1A1PLA2G10PLA2G2A
Diphenylmethane SCHEMBL4409654 0.74 L3MBTL1 (0.55) SLC1A3SLC1A2SLC1A1PLA2G10PLA2G2A
SCHEMBL4411199 0.73 KMT2A (0.44) KMT2AMEN1SIGMAR1ALDH1A1CYP1A2
SCHEMBL28181525 0.73 HPGD (0.58) NPC1RAB9ALMNAL3MBTL1POLB
Bromide SCHEMBL30466577 0.72 NPC1 (0.45) NPC1RAB9AL3MBTL1KMT2ATAAR1
SCHEMBL4421207 0.72 L3MBTL1 (0.43) L3MBTL1POLBALDH1A1HPGD
SCHEMBL27615768 0.72 ALDH1A1 (0.49) NPC1RAB9AL3MBTL1KMT2AALDH1A1
Diphenylmethane SCHEMBL4416804 0.71 L3MBTL1 (0.51) SLC1A3SLC1A2SLC1A1PLA2G10PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed