SCHEMBL441473

SCHEMBL441473

CC1(C)C(C=C(Cl)C(F)(F)F)C1C(=O)OCc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.89

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.89
MEN1 O00255 2/20 0.89
KMT2A Q03164 2/20 0.89
LMNA P02545 4/20 0.44
ATM Q13315 2/20 0.44
ADRA2A P08913 1/20 0.44
CNR1 P21554 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TSHR P16473 1/20 0.38
ALDH1A1 P00352 2/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tefluthrin SCHEMBL20823 0.94 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL14427331 0.94 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL4622567 0.94 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL8769136 0.94 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
SCHEMBL10967859 0.94 TDP1 (0.83) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL1898396 0.94 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL1920781 0.94 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL2740810 0.94 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL21112033 0.94 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL20824 0.94 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7459168-B2 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2008-12-02 US claimed
EP-1352562-B1 Insecticide transpiration apparatus DAINIPPON JOCHUGIKU KK (JP) 2006-11-15 EP claimed
US-6926902-B2 Insecticide transpiration apparatus DAINHON JOCHUGIKU CO., LTD. (JP) 2005-08-09 US claimed
US-20040180070-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2004-09-16 US claimed
EP-1352562-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-10-15 EP claimed
US-20030160062-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-08-28 US claimed
US-9238078-B2 Modified-release pharmaceutical drug composition COATING PLACE, INC. (US) 2016-01-19 US disclosed
US-9125948-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2015-09-08 US disclosed
US-8883213-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2014-11-11 US disclosed
US-8343546-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2013-01-01 US disclosed
US-8329224-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2012-12-11 US disclosed
US-20120064167-A1 MODIFIED-RELEASE PHARMACEUTICAL DRUG COMPOSITION COATING PLACE, INC. (US) 2012-03-15 US disclosed
EP-2413898-A1 MODIFIED-RELEASE PHARMACEUTICAL DRUG COMPOSITION Coating Place, Inc. (US) 2012-02-08 EP disclosed
US-20070140983-A1 Loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle which is separated from the solution and dried before recombining the drug-loaded resin particle with the solution to load more drugs onto the drug-load; controlled release COATING PLACE, INC. (US) 2007-06-21 US disclosed
US-20070059270-A1 Loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle which is separated from the solution and dried before recombining the drug-loaded resin particle with the solution to load more drugs onto the drug-load; controlled release THE COATING PLACE, INC. (US) 2007-03-15 US disclosed
EP-1352562-B1 Insecticide transpiration apparatus DAINIPPON JOCHUGIKU KK (JP) 2006-11-15 EP disclosed
US-6926902-B2 Insecticide transpiration apparatus DAINHON JOCHUGIKU CO., LTD. (JP) 2005-08-09 US disclosed
US-20040180070-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2004-09-16 US disclosed
EP-1352562-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-10-15 EP disclosed
US-20030160062-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040180070-A1 Insecticide transpiration apparatus TIMM13, PIK3C3, ATP5PD TDP1 2733/4885MEN1 4117/4885KMT2A 3655/4885
US-20030160062-A1 Insecticide transpiration apparatus PIK3C3, ACHE, ATP5PD TDP1 1190/4885MEN1 4401/4885KMT2A 4329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.