Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565802 | 0.82 | KDM2B (0.36) | — | |
| SCHEMBL4565895 | 0.79 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1HRH3KDM4E | |
| SCHEMBL2792194 | 0.73 | MEN1 (0.47) | KMT2AMEN1ALDH1A1GAAHRH3 | |
| SCHEMBL25143661 | 0.71 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTHRH3 | |
| SCHEMBL4416910 | 0.69 | TSHR (0.44) | KMT2AMEN1ALDH1A1HRH3 | |
| SCHEMBL2793856 | 0.68 | KMT2A (0.71) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL21569623 | 0.68 | ALDH1A1 (0.68) | KMT2AMEN1ALDH1A1LMNAMAPK1 | |
| SCHEMBL4414919 | 0.67 | OPRD1 (0.35) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL4418076 | 0.67 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10131854 | 0.66 | HPGD (0.54) | ALDH1A1LMNAHTTHRH3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061780-A1 | DIARYL PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Neuromed Pharmaceuticals, Ltd. (CA) | 2009-05-27 | — | — | EP | claimed |
| WO-2008031227-A1 | DIARYL PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2008-03-20 | — | — | WO | claimed |