Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.45 |
| ▸ | PYGM | P11217 | 2/20 | 0.41 |
| ▸ | TK2 | O00142 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145394 | 0.88 | TK1 (0.42) | TK1TK2LMNAADRA1ABLM | |
| SCHEMBL30241268 | 0.88 | LMNA (0.45) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL29875731 | 0.81 | TLR7 (0.36) | TK1CYP3A4 | |
| SCHEMBL7776579 | 0.81 | SLC28A1 (0.40) | TK1TK2P2RY6 | |
| SCHEMBL8846493 | 0.78 | TK1 (0.50) | TK1PYGMTK2LMNASMN1; SMN2 | |
| SCHEMBL27561054 | 0.77 | TK1 (0.43) | TK1TK2LMNAADRA1ATSHR | |
| SCHEMBL8744138 | 0.76 | TK1 (0.41) | TK1TK2LMNAADRA1ABLM | |
| SCHEMBL29950395 | 0.76 | LMNA (0.31) | LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL9396543 | 0.75 | RNASE1 (0.39) | TK1TK2 | |
| SCHEMBL4581987 | 0.75 | TK1 (0.40) | TK1TK2LMNAADRA1ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476694-B | Nucleotide compounds | 奇根科学有限责任公司 | 2022-09-30 | — | — | CN | disclosed |
| US-20090325172-A1 | Modified nucleotides | SOLEXA LIMITED | 2009-12-31 | — | — | US | disclosed |