Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 7/20 | 0.41 |
| ▸ | TK2 | O00142 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145394 | 0.88 | TK1 (0.42) | TK1TK2ALDH1A1LMNAALB | |
| SCHEMBL4581987 | 0.86 | TK1 (0.40) | TK1TK2ALDH1A1LMNAALB | |
| SCHEMBL8744147 | 0.80 | TK1 (0.37) | TK1TK2ALDH1A1LMNAALB | |
| SCHEMBL30241268 | 0.76 | LMNA (0.45) | TK1TK2LMNAADRA1A | |
| SCHEMBL4414876 | 0.76 | TK1 (0.45) | TK1TK2LMNAADRA1ABLM | |
| SCHEMBL27561054 | 0.76 | TK1 (0.43) | TK1TK2ALDH1A1LMNAALB | |
| SCHEMBL9396543 | 0.75 | RNASE1 (0.39) | TK1TK2 | |
| SCHEMBL30583837 | 0.74 | RNASE1 (0.36) | TK1TK2ALDH1A1 | |
| SCHEMBL28238519 | 0.73 | TK1 (0.40) | TK1TK2LMNAALBBLM | |
| SCHEMBL29441948 | 0.72 | ALDH1A1 (0.38) | TK1TK2ALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753002-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026972-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1995-10-12 | — | — | WO | disclosed |