SCHEMBL4415281

SCHEMBL4415281

C=C(C)c1cccc(Br)c1C

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
EDNRA P25101 1/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
PRNP P04156 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6469935 0.83 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10CASP3SENP8
SCHEMBL16962049 0.82 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10CASP3SENP8
SCHEMBL8520695 0.80 NPC1 (0.33) ALDH1A1HPGDHSD17B10SMN1; SMN2NPC1
SCHEMBL3445603 0.79 NPC1 (0.41) ALDH1A1HPGDCASP3SENP8SENP7
SCHEMBL31583030 0.79 NPC1 (0.41) ALDH1A1HPGDCASP3SENP8SENP7
SCHEMBL16955267 0.78 ALDH1A1 (0.32) ALDH1A1HPGDHSD17B10
SCHEMBL715998 0.77 TRPA1 (0.46) ALDH1A1HPGDHSD17B10NPC1RAB9A
SCHEMBL29407046 0.77 TRPA1 (0.46) ALDH1A1HPGDHSD17B10NPC1RAB9A
SCHEMBL25203304 0.77 G6PD (0.31) ALDH1A1SMN1; SMN2NPC1RAB9APRNP
SCHEMBL16955491 0.77 HPGD (0.35) ALDH1A1HPGDHSD17B10CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444302-B1 LEVELLING AGENT AND ANTI-CRATERING AGENT CIBA HOLDING INC (CH) 2009-06-17 EP disclosed
CN-100436552-C Levelling agent and anti-cratering agent EFKA ADDITIVES B V (CH) 2008-11-26 CN disclosed
US-7173084-B2 Levelling agent and anti-cratering agent EFKA ADDITIVES B.V. (NL) 2007-02-06 US disclosed
CN-1571822-A Levelling agent and anti-cratering agent EFKA ADDITIVES B V (NL) 2005-01-26 CN disclosed
US-20040236007-A1 Levelling agent and anti-cratering agent CIBA SPECIALTY CHEMICALS CORPORATION 2004-11-25 US disclosed
EP-1444302-A1 LEVELLING AGENT AND ANTI-CRATERING AGENT Efka Additives B.V. (NL) 2004-08-11 EP disclosed
WO-2003033603-A1 LEVELLING AGENT AND ANTI-CRATERING AGENT EFKA ADDITIVES B.V. (NL) 2003-04-24 WO disclosed
US-4085165-A ISOCYANATE PREPOLYMER, VINYL COMPOUND, POLYAMINE OR POLYETHER CURING AGENT BRIDGESTONE TIRE CO., LTD. (JA) 1978-04-18 US disclosed
US-4075237-A Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof GEIGY CHEMICAL CORPORATION (US) 1978-02-21 US disclosed
US-3949136-A OIL REPELLENTS, WATERPROOFING TEXTILES CIBA-GEIGY AG (CH) 1976-04-06 US disclosed