Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | F2R | P25116 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089840 | 0.84 | PRNP (0.47) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL4443208 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL211283 | 0.83 | TSHR (0.52) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL4415281 | 0.83 | ALDH1A1 (0.36) | ALDH1A1HPGDHSD17B10NPC1RAB9A | |
| SCHEMBL29621571 | 0.83 | TSHR (0.52) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL16962049 | 0.82 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL3710686 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL15351222 | 0.81 | TSHR (0.50) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL16357915 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL1363612 | 0.81 | METAP2 (0.45) | ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110955-A1 | SUBSTITUTED ACETOPHENOME AS MS REAGENTS | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2005-11-24 | — | — | WO | claimed |
| US-20250382290-A1 | SALTS OF SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250270220-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-08-28 | — | — | US | disclosed |
| US-12304915-B2 | SOS1 inhibitors | Mirati Therapeutics, Inc. (US) | 2025-05-20 | — | — | US | disclosed |
| EP-4543450-A1 | SALTS OF SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2025070947-A1 | NOVEL PHTHALAZINE DERIVATIVE COMPOUND AS SOS1 INHIBITOR, AND USE THEREOF | 한미약품 주식회사 | 2025-04-03 | — | — | WO | disclosed |
| CN-119546304-A | Salts of SOS1 inhibitors | 米拉蒂治疗公司 | 2025-02-28 | — | — | CN | disclosed |
| US-20250059182-A1 | SOS1 INHIBITORS | MIRATI THERAPEUTICS, INC | 2025-02-20 | — | — | US | disclosed |
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-20250042857-A1 | SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure | HAIHE BIOPHARMA CO., LTD. (CN) | 2025-02-06 | — | — | US | disclosed |
| WO-2013151923-A1 | PYRIMIDINONE CARBOXAMIDES AS INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013151923-A1 | PYRIMIDINONE CARBOXAMIDES AS INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-10 | — | — | WO | disclosed |
| US-20130217692-A1 | CYCLIC AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| WO-2010131922-A2 | AMIDE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-11-18 | — | — | WO | disclosed |
| WO-2005110955-A1 | SUBSTITUTED ACETOPHENOME AS MS REAGENTS | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2005-11-24 | — | — | WO | disclosed |
| CN-1102586-C | Gamma-butenolide containing aryl substituent at beta position and its solid-phase synthesis process | SHANGHAI INST ORGANIC CHEM (CN) | 2003-03-05 | — | — | CN | disclosed |
| CN-1273245-A | Gamma-butenolide containing aryl substituent at beta position and its solid-phase synthesis process | SHANGHAI INST ORGANIC CHEM (CN) | 2000-11-15 | — | — | CN | disclosed |
| US-4064132-A | ANTIINFLAMMATORY AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-12-20 | — | — | US | disclosed |
| US-4060528-A | ANTIINFLAMMATORY | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-11-29 | — | — | US | disclosed |
| US-4035376-A | ESTERS, AMIDES, HYDROXAMIC ACIDS, ANTIINFLAMMATORY | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042857-A1 | SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure | SOS1, MEN1, BRCA1 | ALDH1A1 2225/4885HPGD 3204/4885HSD17B10 3484/4885 |
| US-20250382290-A1 | SALTS OF SOS1 INHIBITORS | SOS1, SOS2, SOST | ALDH1A1 3158/4885HPGD 3957/4885HSD17B10 3340/4885 |
| US-12304915-B2 | SOS1 inhibitors | SOS1, SOS2, SAV1 | ALDH1A1 3260/4885HPGD 3255/4885HSD17B10 3669/4885 |
| US-20250059182-A1 | SOS1 INHIBITORS | SOS1, SOS2, SOST | ALDH1A1 3367/4885HPGD 3484/4885HSD17B10 3792/4885 |
| US-20250270220-A1 | SOS1 INHIBITORS | SOS1, SOS2, SAV1 | ALDH1A1 3260/4885HPGD 3255/4885HSD17B10 3669/4885 |
| US-20130217692-A1 | CYCLIC AMIDE DERIVATIVE | HDAC10, H1-10, H1-0 | ALDH1A1 538/4885HPGD 3711/4885HSD17B10 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.