SCHEMBL4415633

SCHEMBL4415633

C=Cc1ccccc1OCCOC1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.49
ALDH1A1 P00352 3/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 2/20 0.38
KMT2A Q03164 2/20 0.36
ADRB2 P07550 2/20 0.35
ADRB1 P08588 2/20 0.35
HTR1A P08908 2/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ADRB3 P13945 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4421632 0.98 HPGD (0.47) HPGDALDH1A1HTTSMN1; SMN2KDM4E
SCHEMBL1397150 0.79 HPGD (0.42) HPGDALDH1A1ADRB1HTR1AADRB3
SCHEMBL1988972 0.78 SRC (0.46) HPGD
SCHEMBL1397197 0.77 PTGDR2 (0.47) HPGDALDH1A1HTTSMN1; SMN2KDM4E
SCHEMBL15496945 0.77 HPGD (0.40) HPGDALDH1A1KMT2AHTR1A
SCHEMBL27765738 0.76 ALDH1A1 (0.38) HPGDALDH1A1HTTSMN1; SMN2KDM4E
SCHEMBL19433042 0.75 KDM4E (0.39) ALDH1A1HTTSMN1; SMN2KDM4EKMT2A
SCHEMBL5702609 0.74 HPGD (0.59) HPGDADRB2ADRB1ADRB3
SCHEMBL8335852 0.74 HPGD (0.51) HPGDALDH1A1SMN1; SMN2ADRB2ADRB1
SCHEMBL8057330 0.73 ALDH1A1 (0.48) HPGDALDH1A1HTTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1270553-B1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORP (JP) 2009-11-18 EP disclosed
US-6908722-B2 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORPORATION (JP) 2005-06-21 US disclosed
US-20030113658-A1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORPORATION (JP) 2003-06-19 US disclosed
EP-1270553-A2 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR Corporation (JP) 2003-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030113658-A1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition ASIC1, PFAS, RARA HPGD 3253/4885ALDH1A1 1216/4885HTT 4125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.