Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305294 | 0.81 | MEN1 (0.42) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL4417724 | 0.72 | NR4A1 (0.40) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL28783429 | 0.71 | KDM4E (0.37) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL18590886 | 0.69 | MEN1 (0.33) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL22175514 | 0.68 | MEN1 (0.49) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL12775945 | 0.66 | POLB (0.33) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL650304 | 0.64 | SIRT2 (0.39) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL1506854 | 0.62 | POLB (0.42) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL7906187 | 0.62 | MEN1 (0.44) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL15119748 | 0.61 | PDK2 (0.46) | ALDH1A1CYP1A2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646609-B1 | NOVEL CHEMILUMINESCENT COMPOUNDS AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2009-10-14 | — | — | EP | disclosed |
| US-7262306-B2 | Chemiluminescent compounds and their use | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-20060199223-A1 | storage stability; immunoassays | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2006-09-07 | — | — | US | disclosed |
| EP-1496050-A1 | Novel chemiluminescent compounds and their use | Roche Diagnostics GmbH (DE) | 2005-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199223-A1 | storage stability; immunoassays | SHBG, SELL, XIAP | ALDH1A1 128/4885CYP1A2 1596/4885CYP2C9 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.