Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415865 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL650304 | 0.78 | SIRT2 (0.39) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL4417724 | 0.76 | NR4A1 (0.40) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL28783429 | 0.75 | KDM4E (0.37) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL18590886 | 0.73 | MEN1 (0.33) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL4296863 | 0.72 | ALDH1A1 (0.42) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL22175514 | 0.72 | MEN1 (0.49) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL12775945 | 0.70 | POLB (0.33) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL31575390 | 0.70 | MEN1 (0.33) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL876222 | 0.67 | MAPT (0.55) | MEN1KMT2AMAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503437-B2 | 1,1-dimethyl-2-[(E)-2-phenylethenyl]-1H-benzo[e]indole derivatives and uses thereof | KAUNAS UNIVERSITY OF TECHNOLOGY (LT) | 2025-12-23 | — | — | US | disclosed |
| US-20250066301-A1 | 1,1-Dimethyl-2-[(E)-2-phenylethenyl]-1H-benzo[e]indole derivatives and uses thereof | PALACKY UNIVERSITY OLOMOUC (CZ) | 2025-02-27 | — | — | US | disclosed |
| WO-2023210645-A1 | ICG LIPID DERIVATIVE, AND LIPID MICROPARTICLES EACH CONTAINING SAME | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2023-11-02 | — | — | WO | disclosed |
| US-20230114083-A1 | PHOTOACOUSTIC IMAGING AGENT | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-04-13 | — | — | US | disclosed |
| WO-2022163807-A1 | PHOTOACOUSTIC IMAGING AGENT | 国立大学法人北海道大学 | 2022-08-04 | — | — | WO | disclosed |
| US-20210393807-A1 | PHOTOACOUSTIC VOLTAGE-SENSITIVE DYES FOR IN VIVO IMAGING | UNIVERSITY OF CONNECTICUT | 2021-12-23 | — | — | US | disclosed |
| WO-2020181929-A1 | PREPARATION METHOD FOR HEPTAMETHYLBENZYLINDOLE CYANINE DYE AND APPLICATION THEREOF | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 2020-09-17 | — | — | WO | disclosed |
| EP-2682131-B1 | SWITCHING-TYPE FLUORESCENT NANOPARTICLE PROBE, AND FLUORESCENT MOLECULAR IMAGING METHOD USING SAME | UNIV KYOTO (JP) | 2020-05-13 | — | — | EP | disclosed |
| US-10598834-B2 | Near-infrared light blocking optical filter having high visible light transmission and an imaging device using the optical filter | AGC Inc. (JP) | 2020-03-24 | — | — | US | disclosed |
| WO-2020047477-A1 | CATIONIC COMPOUNDS FOR DELIVERY OF NUCLEIC ACIDS | CITY OF HOPE (US) | 2020-03-05 | — | — | WO | disclosed |
| US-5391741-A | Can be vacuum deposited; storage stability, high absorbance in near infrared | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0350026-B1 | Infrared filter dye for photographic element | EASTMAN KODAK CO (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5268486-A | Water soluble luminescent dye | CARNEGIE-MELLON UNVERSITY (US) | 1993-12-07 | — | — | US | disclosed |
| EP-0568877-A1 | Squarylium compounds and optical information recording medium using the same | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-11-10 | — | — | EP | disclosed |
| EP-0288076-B1 | INFRARED FILTER DYES FOR PHOTOGRAPHIC ELEMENTS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1991-09-04 | — | — | EP | disclosed |
| US-4933269-A | COOL IMAGE TONE | EASTMAN KODAK COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0350026-A2 | Infrared filter dye for photographic element | EASTMAN KODAK COMPANY (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4876181-A | ANTIHALATION, ANTISTAINING AGENTS; CYANINE DYES OF INDOLE, BENZINDOLE OR NAPHTHINDOLE TYPES | EASTMAN KODAK COMPANY (US) | 1989-10-24 | — | — | US | disclosed |
| US-4871656-A | SULFO-SUBSTITUTED INDOLE, BENZINDOLE OR NAPHTHINDOLE TRICARBOCYANINE DYE | EASTMAN KODAK COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0288076-A2 | Infrared filter dyes for photographic elements | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12503437-B2 | 1,1-dimethyl-2-[(E)-2-phenylethenyl]-1H-benzo[e]indole derivatives and uses thereof | IDO1, IDO2, ALDH1B1 | MEN1 636/4885KMT2A 1657/4885MAPT 2803/4885 |
| US-20210393807-A1 | PHOTOACOUSTIC VOLTAGE-SENSITIVE DYES FOR IN VIVO IMAGING | KCNN2, KCNN1, KCNN3 | MEN1 2750/4885KMT2A 3916/4885MAPT 1828/4885 |
| US-20230114083-A1 | PHOTOACOUSTIC IMAGING AGENT | PTAFR, KDR, RXFP2 | MEN1 2883/4885KMT2A 4495/4885MAPT 3940/4885 |
| US-20250066301-A1 | 1,1-Dimethyl-2-[(E)-2-phenylethenyl]-1H-benzo[e]indole derivatives and uses thereof | IDO1, IDO2, ALDH1B1 | MEN1 636/4885KMT2A 1657/4885MAPT 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.