Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | METAP2 | P50579 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305294 | 0.78 | MEN1 (0.42) | ALDH1A1SMN1; SMN2MAPTKDM4ECYP2A6 | |
| SCHEMBL4296863 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EPOLBMEN1 | |
| SCHEMBL4296989 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EPOLBMEN1 | |
| SCHEMBL15066792 | 0.74 | AR (0.36) | HTR2BSIGMAR1ALDH1A1MAPTKDM4E | |
| SCHEMBL6539867 | 0.74 | AR (0.38) | HTR2BSIGMAR1MAPTPOLBPGR | |
| SCHEMBL3433055 | 0.69 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL3753314 | 0.68 | NCEH1 (0.40) | SIRT2HTR2BSIGMAR1ERN1ALDH1A1 | |
| SCHEMBL56836 | 0.65 | CYP2A6 (0.57) | ERN1ALDH1A1MAPTKDM4ECYP2A6 | |
| SCHEMBL26922538 | 0.65 | BRD4 (0.45) | HTR2BMAPTPOLBPGRTP53 | |
| SCHEMBL650303 | 0.65 | MEN1 (0.62) | SIRT2HTR2BSIGMAR1ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119816-B2 | Merocyanine dye and use thereof | TAIWAN FLUORO TECHNOLOGY CO., LTD. (TW) | 2012-02-21 | — | — | US | disclosed |
| US-20110165518-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2011-07-07 | — | — | US | disclosed |
| US-20110165518-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2011-07-07 | — | — | US | disclosed |
| US-20070085074-A1 | Merocyanine dye and use thereof | TUBE SMITH TECHNOLOGY CO.,LTD. (TW) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070085074-A1 | Merocyanine dye and use thereof | NR1I2, SLCO2B1, SLCO2A1 | SIRT2 1236/4885HTR2B 608/4885SIGMAR1 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.