Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415896 | 1.00 | HSD17B3 (0.41) | HSD17B3PKMHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL7199687 | 0.86 | PKM (0.43) | HSD17B3PKMHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL9110697 | 0.86 | HPGD (0.50) | PKMHPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7199685 | 0.86 | PKM (0.43) | HSD17B3PKMHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL7065540 | 0.84 | L3MBTL1 (0.42) | HSD17B3HPGDL3MBTL1SMN1; SMN2STS | |
| SCHEMBL4419356 | 0.82 | HSD17B3 (0.58) | HSD17B3HPGDL3MBTL1SMN1; SMN2STS | |
| SCHEMBL1476583 | 0.81 | PKM (0.46) | PKML3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL618280 | 0.81 | PKM (0.46) | PKML3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13541031 | 0.81 | CES2 (0.42) | HPGDL3MBTL1ALDH1A1MAPT | |
| SCHEMBL16581264 | 0.78 | DYRK1A (0.41) | KDM4EHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395615-B1 | OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE | BASF SE (DE) | 2009-10-21 | — | — | EP | disclosed |
| US-7189489-B2 | Oxime ester photoiniators having a combined structure | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-03-13 | — | — | US | disclosed |
| US-20040170924-A1 | Oxime ester photoiniators having a combined structure | CIBA CORPORATION | 2004-09-02 | — | — | US | disclosed |