SCHEMBL4419356

SCHEMBL4419356

CCCC(=O)c1ccc(Sc2ccc(C(=O)c3ccc(Sc4ccc(C(=O)CCC)cc4)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 8/20 0.58
HPGD P15428 5/20 0.53
L3MBTL1 Q9Y468 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
LMNA P02545 2/20 0.48
STS P08842 1/20 0.46
HTR7 P34969 1/20 0.44
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7195006 0.94 HSD17B3 (0.64) HSD17B3HPGDL3MBTL1SMN1; SMN2LMNA
SCHEMBL14571009 0.93 LMNA (0.52) HSD17B3HPGDL3MBTL1SMN1; SMN2LMNA
SCHEMBL242996 0.87 L3MBTL1 (0.66) HSD17B3HPGDL3MBTL1SMN1; SMN2LMNA
SCHEMBL17946314 0.86 HSD17B3 (0.55) HSD17B3HPGDL3MBTL1SMN1; SMN2LMNA
SCHEMBL10872117 0.83 HSD17B3 (0.67) HSD17B3HPGDL3MBTL1LMNASTS
SCHEMBL4415892 0.82 HSD17B3 (0.41) HSD17B3HPGDL3MBTL1SMN1; SMN2LMNA
SCHEMBL4415896 0.82 HSD17B3 (0.41) HSD17B3HPGDL3MBTL1SMN1; SMN2LMNA
SCHEMBL26254861 0.82 HSD17B3 (0.82) HSD17B3HPGDL3MBTL1SMN1; SMN2STS
SCHEMBL10871658 0.81 HSD17B3 (0.68) HSD17B3HPGDL3MBTL1LMNASTS
SCHEMBL4423910 0.81 L3MBTL1 (0.57) HSD17B3L3MBTL1LMNATHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395615-B1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE BASF SE (DE) 2009-10-21 EP disclosed
US-7189489-B2 Oxime ester photoiniators having a combined structure CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-03-13 US disclosed
US-20040170924-A1 Oxime ester photoiniators having a combined structure CIBA CORPORATION 2004-09-02 US disclosed
EP-1395615-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE Ciba SC Holding AG (CH) 2004-03-10 EP disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 WO disclosed