Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.58 |
| ▸ | CBR1 | P16152 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176771 | 0.89 | TTR (0.49) | TTRMAPTHPGDNR1I2LMNA | |
| Soneclosan SCHEMBL29359126 | 0.89 | TTR (0.66) | TTRMAPTHPGDNR1I2LMNA | |
| Soneclosan SCHEMBL465591 | 0.89 | TTR (0.66) | TTRMAPTHPGDNR1I2LMNA | |
| Soneclosan SCHEMBL28242916 | 0.88 | MAPT (0.49) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL7179614 | 0.85 | ALOX15 (0.50) | TTRMAPTHPGDLMNAMEN1 | |
| SCHEMBL7176805 | 0.82 | TTR (0.58) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL14157301 | 0.82 | HPGD (0.58) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL13778174 | 0.82 | TTR (0.58) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL10885322 | 0.82 | MAPK1 (0.64) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL7182380 | 0.82 | TTR (0.58) | TTRMAPTHPGDNR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638578-A4 | HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE | ANACOR PHARMACEUTICALS INC (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1638578-A2 | HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE | Anacor Pharmaceuticals, Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005013892-A2 | HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE | ANACOR PHARMACEUTICALS, INC. (US) | 2005-02-17 | — | — | WO | disclosed |
| EP-1349453-A2 | BIOCIDE COMPOSITIONS AND METHODS AND SYSTEMS EMPLOYING SAME | THE PROCTER & GAMBLE COMPANY (US) | 2003-10-08 | — | — | EP | disclosed |
| US-20020068014-A1 | Antibacterial agents and compositions, methods and systems employing same | PROCTER & GAMBLE COMPANY, THE | 2002-06-06 | — | — | US | disclosed |
| US-20020014178-A1 | Biocide compositions and methods and systems employing same | PROCTER & GAMBLE COMPANY, THE | 2002-02-07 | — | — | US | disclosed |
| WO-2002005643-A2 | BIOCIDE COMPOSITIONS AND METHODS AND SYSTEMS EMPLOYING SAME | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |
| WO-2001060157-A2 | ANTIBACTERIAL AGENTS AND COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-08-23 | — | — | WO | disclosed |
| US-5741663-A | MEASURING MICROBIAL GROWTH IN FRESH ANIMAL PRODUCTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1997039140-A1 | SELECTIVE ADDITIVE AND MEDIA FOR $i(PSEUDOMONAS FLUORESCENS) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1997-10-23 | — | — | WO | disclosed |
| US-4326978-A | A HALOGENATED O-HYDROXY- DIPHENYL ETHER, AND MAGNESIUM SILICATE TO INHIBIT DISCOLORATION | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4111844-A | 2,4,4'-TRICHLORO-2'-HYDROXY-DIPHENYL ETHER, ANIONIC SURFACTANT, WATER | CIBA-GEIGY CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068014-A1 | Antibacterial agents and compositions, methods and systems employing same | SPOUT1, PGLS, TLR6 | TTR 2946/4885MAPT 4156/4885HPGD 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.