Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24476657 | 0.90 | ALDH1A1 (0.44) | EPHX1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL21998027 | 0.86 | HPGD (0.44) | EPHX1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL4035282 | 0.86 | HPGD (0.48) | EPHX1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL3142012 | 0.86 | EPHX1 (0.49) | EPHX1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL26094030 | 0.86 | NR1H2 (0.46) | EPHX1HPGDALDH1A1PDE4BPRMT5 | |
| SCHEMBL792038 | 0.84 | HPGD (0.49) | EPHX1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL1576027 | 0.82 | HPGD (0.50) | EPHX1HPGDRECQLPTPN2PTPN1 | |
| SCHEMBL2149148 | 0.82 | HPGD (0.50) | EPHX1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL29575514 | 0.82 | PRMT5 (0.42) | EPHX1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL6132702 | 0.82 | HPGD (0.47) | EPHX1HPGDPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085082-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2026-03-26 | — | — | US | disclosed |
| EP-4637760-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | Imago Biosciences Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2025072686-A1 | KRAS G12D MUTATION TARGETING COMPOUNDS | SUMMIT THERAPEUTICS INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2024137358-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024137358-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| US-20090325924-A1 | GPCR Agonists | PROSIDION LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| EP-1907383-A1 | GPCR AGONISTS | Prosidion Limited (GB) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007003960-A1 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325924-A1 | GPCR Agonists | GPR119, GCGR, GPR27 | EPHX1 1312/4885HPGD 1902/4885ALDH1A1 1059/4885 |
| US-20260085082-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | KDM1B, KDM1A, KDM5C | EPHX1 2884/4885HPGD 4013/4885ALDH1A1 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.