Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | TXNRD1 | Q16881 | 6/20 | 0.61 |
| ▸ | TXNRD3 | Q86VQ6 | 6/20 | 0.61 |
| ▸ | TXNRD2 | Q9NNW7 | 6/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PYGB | P11216 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gamma-Cyclodextrin SCHEMBL3819072 | 1.00 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| Betadex SCHEMBL5507793 | 0.98 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL14479710 | 0.91 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| Betadex SCHEMBL4654147 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| Betadex SCHEMBL28281939 | 0.88 | ALDH1A1 (0.87) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| Gamma-Cyclodextrin SCHEMBL28276059 | 0.88 | ALDH1A1 (0.87) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| Gamma-Cyclodextrin SCHEMBL25455531 | 0.86 | ALDH1A1 (1.00) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| Gamma-Cyclodextrin SCHEMBL25455463 | 0.86 | ALDH1A1 (1.00) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| Betadex SCHEMBL23188251 | 0.86 | ALDH1A1 (1.00) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| Betadex SCHEMBL24109285 | 0.86 | ALDH1A1 (1.00) | ALDH1A1TSHRLMNATDP1TXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117752662-A | Formulations of 4- (7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl) -benzonitrile | 博士伦爱尔兰有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-111568906-B | Formulations of 4- (7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl) -benzonitrile | 诺华股份有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-115487138-A | Allopregnanolone injection and preparation method thereof | 北京万全德众医药生物技术有限公司 | 2022-12-20 | — | — | CN | claimed |
| US-20220000776-A1 | PARENTERAL DOSAGE FORM OF AMIODARONE | SUN PHARMACEUTICAL IND LTD (IN) | 2022-01-06 | — | — | US | claimed |
| US-11166911-B2 | Parenteral dosage form of amiodarone | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2021-11-09 | — | — | US | claimed |
| CN-110215430-A | The nitroglycerin pharmaceutical composition of new injectable | 刘力 | 2019-09-10 | — | — | CN | claimed |
| US-20190070110-A1 | PARENTERAL DOSAGE FORM OF AMIODARONE | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2019-03-07 | — | — | US | claimed |
| CN-108712909-A | Oritavancin preparation | 梅琳塔治疗公司 | 2018-10-26 | — | — | CN | claimed |
| CN-108472379-A | Formulations for reducing polysorbate degradation | 豪夫迈·罗氏有限公司 | 2018-08-31 | — | — | CN | claimed |
| CN-105431458-A | Cyclodextrin | CURADEV PHARMA PVT LTD | 2016-03-23 | — | — | CN | claimed |
| US-20120065186-A1 | ANTIMICROBIAL COMPOSITIONS | RIB-X PHARMACEUTICALS, INC. | 2012-03-15 | — | — | US | claimed |
| EP-2373166-A2 | ANTIMICROBIAL COMPOSITIONS | Rib-X Pharmaceuticals, Inc. (US) | 2011-10-12 | — | — | EP | claimed |
| WO-2010056872-A2 | ANTIMICROBIAL COMPOSITIONS | RIB-X PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | claimed |
| US-20050215520-A1 | Complex of organic medicines and beta-cyclodextrin derivatives and its preparing process | ADVANCED LIU'S PHARMA TECH, LLC | 2005-09-29 | — | — | US | claimed |
| EP-1514877-A1 | COMPLEX OF ORGANIC MEDICINES AND BETA-CYCLODEXTRIN DERIVATIVES AND ITS PREPARING PROCESS | Liu, Yunqing (CN) | 2005-03-16 | — | — | EP | claimed |
| US-6407079-B1 | INCLUSION COMPOUND ETHERIFIED CYCLODEXTRIN; NONTOXIC, STABILITY | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-06-18 | — | — | US | claimed |
| US-4920214-A | Process for producing modified cyclodextrins | AMERICAN MAIZE-PRODUCTS COMPANY (US) | 1990-04-24 | — | — | US | claimed |
| EP-4377327-A1 | CRYSTALLINE FORMS OF A NEUROACTIVE STEROID | Sage Therapeutics, Inc. (US) | 2024-06-05 | — | — | EP | disclosed |
| CN-1047289-A | (sulfo-) morpholinyl of rhinovirus and the preparation method of piperazinyl alkylphenol ethers | HANSSEN PHARMACEUTICA N V (BE) | 1990-11-28 | — | — | CN | disclosed |
| CN-1033274-A | The preparation method of new Pyridazinyl amine derivative | JANSSEN PHARMACEUTICA NV (BE) | 1989-06-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000776-A1 | PARENTERAL DOSAGE FORM OF AMIODARONE | STS, ABCB11, CYP2D6 | ALDH1A1 1493/4885TSHR 3835/4885LMNA 3538/4885 |
| US-11166911-B2 | Parenteral dosage form of amiodarone | STS, ABCB11, CYP2D6 | ALDH1A1 1493/4885TSHR 3835/4885LMNA 3538/4885 |
| US-20120065186-A1 | ANTIMICROBIAL COMPOSITIONS | NOD2, QPCT, IFNG | ALDH1A1 2608/4885TSHR 4804/4885LMNA 2946/4885 |
| US-20190070110-A1 | PARENTERAL DOSAGE FORM OF AMIODARONE | STS, ABCB11, CYP2D6 | ALDH1A1 1493/4885TSHR 3835/4885LMNA 3538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.