Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032046 | 0.90 | CCR2 (0.36) | KCNH2ALDH1A1F10 | |
| SCHEMBL4415059 | 0.90 | CCR2 (0.35) | KMT2AKCNH2MCHR1TLR7F10 | |
| SCHEMBL4424128 | 0.88 | CCR2 (0.35) | KMT2ACSNK2A2CSNK2A1ALDH1A1F10 | |
| SCHEMBL4427802 | 0.84 | F10 (0.34) | KMT2AKCNH2MCHR1F10 | |
| SCHEMBL4421724 | 0.82 | F10 (0.36) | KMT2AKCNH2MCHR1F10 | |
| SCHEMBL4416711 | 0.82 | CNR1 (0.37) | KMT2AKCNH2MCHR1F10 | |
| SCHEMBL4417585 | 0.82 | CNR1 (0.40) | KMT2AF10 | |
| SCHEMBL4420896 | 0.82 | CCR2 (0.36) | KMT2AKCNH2MCHR1F10 | |
| SCHEMBL4413722 | 0.82 | F10 (0.35) | KMT2AKCNH2MCHR1ALDH1A1F10 | |
| SCHEMBL4428598 | 0.81 | F10 (0.36) | KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606255-B1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2009-11-11 | — | — | EP | claimed |