SCHEMBL4409653

SCHEMBL4409653

NNC(=O)CCNc1ccc(Cc2ccc(NCCC(=O)NN)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 3/20 0.43
MAPK1 P28482 1/20 0.43
MPI P34949 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 2/20 0.40
LTA4H P09960 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 2/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
CYP2C9 P11712 1/20 0.39
HIF1A Q16665 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4071505 0.82 MPO (0.50) POLBL3MBTL1ALDH1A1MAPTLMNA
SCHEMBL4249311 0.82 ALDH1A1 (0.48) POLBL3MBTL1ALDH1A1MAPTLMNA
SCHEMBL1627561 0.81 L3MBTL1 (0.65) POLBL3MBTL1ALDH1A1MAPTLMNA
SCHEMBL14184803 0.79 L3MBTL1 (0.57) POLBL3MBTL1ALDH1A1MAPTMAPK1
SCHEMBL11510935 0.76 POLB (0.51) POLBL3MBTL1ALDH1A1MAPTMAPK1
SCHEMBL8432625 0.75 FFAR1 (0.58) POLBALDH1A1MAPTLTA4HMEN1
Diphenylmethane SCHEMBL4416804 0.75 L3MBTL1 (0.51) L3MBTL1LTA4HCYP1A2CYP3A4CYP2D6
SCHEMBL4072414 0.72 MPO (0.47) L3MBTL1ALDH1A1MAPTLMNACYP1A2
SCHEMBL10457154 0.71 L3MBTL1 (0.61) L3MBTL1ALDH1A1MAPTLTA4HCYP1A2
SCHEMBL4081019 0.71 PRSS1 (0.49) L3MBTL1ALDH1A1MAPTLMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed