Biphenyl

Biphenyl

SCHEMBL4413773

NNC(=O)CCNCCC(=O)NN.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.55
CYP1A2 P05177 2/20 0.51
CYP3A4 P08684 2/20 0.51
CYP2D6 P10635 2/20 0.51
CYP2C19 P33261 2/20 0.51
KMT2A Q03164 3/20 0.45
ALDH1A1 P00352 2/20 0.44
NPC1 O15118 1/20 0.44
MITF O75030 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
KDM4E B2RXH2 2/20 0.43
KDM5C P41229 1/20 0.43
PHF8 Q9UPP1 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43
DRD2 P14416 1/20 0.43
DRD4 P21917 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL4409529 0.88 KDM4E (0.54) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Diphenylmethane SCHEMBL4416804 0.85 L3MBTL1 (0.51) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Biphenyl SCHEMBL4411169 0.84 L3MBTL1 (0.58) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL4421124 0.79 KDM4E (0.52) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL1627561 0.77 L3MBTL1 (0.65) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL4411167 0.76 ALDH1A1 (0.51) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Biphenyl SCHEMBL5574503 0.74 ALDH1A1 (0.50) KMT2AALDH1A1NPC1HTTRAB9A
SCHEMBL6869213 0.73 KMT2A (0.66) KMT2AALDH1A1HTTKDM4EMEN1
SCHEMBL4411483 0.73 HDAC3 (0.44) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL960759 0.73 CTSD (0.65) L3MBTL1CYP1A2CYP3A4CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed