SCHEMBL4417022

SCHEMBL4417022

CCOC(=O)CNCCNS(=O)(=O)c1nnc(C)s1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA12 O43570 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
ALDH1A1 P00352 5/20 0.38
HPGD P15428 2/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 1/20 0.37
HSD11B1 P28845 2/20 0.35
LTA4H P09960 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4418662 0.82 LTA4H (0.43) ALDH1A1HPGDLTA4H
SCHEMBL4413761 0.80 MAPT (0.41) ALDH1A1HPGDGAAMAPTKMT2A
SCHEMBL4423896 0.78 KMT2A (0.38) ALDH1A1HPGDMAPTKMT2ALTA4H
SCHEMBL4413837 0.77 MAPT (0.45) ALDH1A1HPGDGAAMAPTKMT2A
SCHEMBL4412465 0.77 CSNK2A2 (0.47) ALDH1A1GAAMAPTKMT2A
SCHEMBL4411288 0.76 DDX3X (0.42) ALDH1A1HPGDGAAMAPT
SCHEMBL609992 0.76 MAPK1 (0.50) CA1CA2CA12CA4CA7
SCHEMBL2648409 0.75 ALDH1A1 (0.48) CA1CA2CA12CA3CA4
SCHEMBL4414575 0.74 ALDH1A1 (0.49) ALDH1A1HPGDGAAMAPTKMT2A
SCHEMBL4412181 0.73 KMT2A (0.39) ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651642-B1 PNA MONOMER AND PRECURSOR PANAGENE INC (KR) 2009-11-04 EP disclosed
US-7211668-B2 PNA monomer and precursor PANAGENE, INC. (KR) 2007-05-01 US disclosed
EP-1651642-A4 PNA MONOMER AND PRECURSOR PANAGENE INC (KR) 2006-11-29 EP disclosed
EP-1651642-A1 PNA MONOMER AND PRECURSOR Panagene Inc. (KR) 2006-05-03 EP disclosed
US-20050026930-A1 PNA monomer and precursor PANAGENE, INC. (KR) 2005-02-03 US disclosed
WO-2005009998-A1 PNA MONOMER AND PRECURSOR PANAGENE INC. (US) 2005-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026930-A1 PNA monomer and precursor RNGTT, POLL, NSUN3 CA1 1963/4885CA2 3196/4885CA12 3059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.