Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552332 | 0.86 | TAS2R14 (0.49) | PKMALDH1A1NPSR1L3MBTL1FKBP1A | |
| SCHEMBL13972857 | 0.86 | TAS2R14 (0.49) | PKMALDH1A1NPSR1L3MBTL1FKBP1A | |
| SCHEMBL4422262 | 0.85 | NPSR1 (0.40) | NPSR1L3MBTL1FKBP1ACA1CA2 | |
| SCHEMBL6030159 | 0.85 | NPSR1 (0.41) | SMN1; SMN2NPSR1L3MBTL1FKBP1ATP53 | |
| SCHEMBL4410698 | 0.84 | NPSR1 (0.41) | NPSR1L3MBTL1FKBP1AMAPTCA1 | |
| SCHEMBL4423028 | 0.82 | CA1 (0.41) | ALDH1A1NPSR1L3MBTL1TP53MAPT | |
| SCHEMBL13973317 | 0.82 | CA1 (0.41) | ALDH1A1NPSR1L3MBTL1TP53MAPT | |
| SCHEMBL4414908 | 0.82 | PKM (0.48) | SMN1; SMN2PKMALDH1A1FKBP1ACA1 | |
| SCHEMBL4415190 | 0.82 | CA1 (0.41) | NPSR1L3MBTL1FKBP1ACA1CA2 | |
| SCHEMBL4422266 | 0.81 | HTR6 (0.40) | NPSR1L3MBTL1FKBP1ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663983-B1 | N-SUBSTITUTED, 6,8-DIALKOXY-1,2,3,4-TETRAHYDRO-1H-ISOQUINOLINE AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2009-01-21 | — | — | EP | disclosed |
| US-20050070570-A1 | Novel potassium channels modulators | 4SC AG (DE) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070570-A1 | Novel potassium channels modulators | HCN4, KCNA4, KCNN4 | SMN1; SMN2 4121/4885PKM 1619/4885ALDH1A1 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.