SCHEMBL4417481

SCHEMBL4417481

CCOC(=O)CC(O)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EED O75530 1/20 0.45
RBBP4 Q09028 1/20 0.45
SUZ12 Q15022 1/20 0.45
EZH2 Q15910 1/20 0.45
AEBP2 Q6ZN18 1/20 0.45
HPGD P15428 1/20 0.45
GPR119 Q8TDV5 4/20 0.45
DPP4 P27487 1/20 0.45
IDO1 P14902 3/20 0.44
RECQL P46063 1/20 0.43
EPHX1 P07099 1/20 0.43
GAA P10253 1/20 0.42
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42
USP2 O75604 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19554688 0.86 GPR119 (0.50) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL1575174 0.86 GPR119 (0.50) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL30922717 0.86 ALDH1A1 (0.46) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL12082901 0.85 DPP4 (0.55) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL13630780 0.84 EPHX1 (0.50) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL13316244 0.83 DPP4 (0.42) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL3257440 0.83 HPGD (0.51) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL4403100 0.81 HPGD (0.50) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL1693087 0.81 HPGD (0.50) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL1873727 0.80 EPHX1 (0.50) EEDRBBP4SUZ12EZH2AEBP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090325924-A1 GPCR Agonists PROSIDION LIMITED (GB) 2009-12-31 US disclosed
US-20090325924-A1 GPCR Agonists PROSIDION LIMITED (GB) 2009-12-31 US disclosed
US-20090325924-A1 GPCR Agonists PROSIDION LIMITED (GB) 2009-12-31 US disclosed
WO-2007003960-A1 GPCR AGONISTS PROSIDION LIMITED (GB) 2007-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090325924-A1 GPCR Agonists GPR119, GCGR, GPR27 EED 4284/4885RBBP4 3254/4885SUZ12 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.