Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13597508 | 0.81 | — | — | |
| SCHEMBL4641210 | 0.77 | — | — | |
| SCHEMBL9848753 | 0.77 | ALDH1A1 (0.36) | THRBLMNA | |
| SCHEMBL11098658 | 0.76 | THRB (0.31) | THRB | |
| SCHEMBL3880423 | 0.75 | — | — | |
| SCHEMBL8906574 | 0.74 | THRB (0.33) | THRBLMNA | |
| SCHEMBL31347979 | 0.74 | ADH1B (0.42) | LMNA | |
| SCHEMBL10567526 | 0.74 | — | — | |
| SCHEMBL8829654 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL11219107 | 0.74 | ADH1B (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090326239-A1 | FERMENTATIVE PREPARATION PROCESS FOR AND CRYSTAL FORMS OF CYTOSTATICS | HOFMANN HANS | 2009-12-31 | — | — | US | disclosed |
| US-20070197611-A1 | Fermentative preparation process for and crystal forms of cytostatics | HOFMANN HANS | 2007-08-23 | — | — | US | disclosed |
| US-7101702-B2 | Fermentative preparation process for and crystal forms of cytostatics | NOVARTIS AG (CH) | 2006-09-05 | — | — | US | disclosed |
| US-6656711-B2 | Concentrating epothilones in culture from Sorangium strains obtained by mutagenesis; antitumor agents | NOVARTIS AG (CH) | 2003-12-02 | — | — | US | disclosed |
| US-20030220379-A1 | Fermentative preparation process for and crystal forms of cytostatics | HOFMANN HANS (CH) | 2003-11-27 | — | — | US | disclosed |
| US-20020165256-A1 | Fermentative preparation process for and crystal forms of cytostatics | HOFMANN HANS (CH) | 2002-11-07 | — | — | US | disclosed |
| US-6194181-B1 | PRODUCING EPOTHIOLONES IN A CULTURE MEDIUM BY PROVIDING MICROORGANISMS SUCH AS MYXOBACTERIA WHICH PRODUCE EPOTHIOLONES, AND ADDING A COMPLEX-FORMING AGENT SOLUBLE IN THE CULTURE MEDIUM, SUCH AS CYCLODEXTRINS; ANTITUMOR AGENTS | NOVARTIS AG (CH) | 2001-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220379-A1 | Fermentative preparation process for and crystal forms of cytostatics | TALDO1, PYCR1, THPO | THRB 3007/4885LMNA 3638/4885 |
| US-20020165256-A1 | Fermentative preparation process for and crystal forms of cytostatics | TALDO1, PYCR1, THPO | THRB 3007/4885LMNA 3638/4885 |
| US-20070197611-A1 | Fermentative preparation process for and crystal forms of cytostatics | TALDO1, PYCR1, THPO | THRB 3057/4885LMNA 3593/4885 |
| US-20090326239-A1 | FERMENTATIVE PREPARATION PROCESS FOR AND CRYSTAL FORMS OF CYTOSTATICS | TALDO1, PYCR1, THPO | THRB 3007/4885LMNA 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.