Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 5/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.34 |
| ▸ | CPT2 | P23786 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999848 | 0.90 | HTR6 (0.39) | FABP4HTR6CYP3A4LMNATSHR | |
| SCHEMBL1997934 | 0.83 | ALDH1A1 (0.36) | HTR6CYP3A4CPT1ACPT1BCPT2 | |
| SCHEMBL1998511 | 0.81 | FABP4 (0.37) | FABP4HTR6MET | |
| SCHEMBL1995809 | 0.81 | HTR6 (0.43) | FABP4HTR6CYP3A4MET | |
| Trifluoroacetic Acid SCHEMBL1995689 | 0.80 | HTR6 (0.39) | FABP4HTR6CYP3A4LMNATSHR | |
| Trifluoroacetic Acid SCHEMBL4562899 | 0.79 | CPT2 (0.31) | CPT1ACPT1BCPT2 | |
| SCHEMBL1997745 | 0.76 | TSHR (0.39) | CPT1ACPT1BCPT2LMNATSHR | |
| SCHEMBL4563388 | 0.74 | MCOLN3 (0.39) | FABP4CPT1ACPT1BCPT2TSHR | |
| SCHEMBL1996300 | 0.73 | HTR6 (0.35) | HTR6TSHR | |
| Trifluoroacetic Acid SCHEMBL1998592 | 0.73 | CPT1A (0.33) | FABP4HTR6CYP3A4CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091953-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4]OXAZEPINO [6, 7-E]INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (publ) (SE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008054288-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4] OXAZEPINO [6, 7-E] INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (PUBL) (SE) | 2008-05-08 | — | — | WO | disclosed |