Nitric Acid

Nitric Acid

SCHEMBL44182

O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])OCC(O)CO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
GSR P00390 1/20 0.32
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL7262025 1.00 CA5A (0.35) CA5ACA5BALDH1A1LMNASMN1; SMN2
Nitric Acid SCHEMBL15562819 1.00 CA5A (0.35) CA5ACA5BALDH1A1LMNASMN1; SMN2
SCHEMBL62389 0.96
SCHEMBL9420277 0.96 ALDH1A1 (0.37) ALDH1A1LMNASMN1; SMN2GSRKDM4E
Ethylene SCHEMBL11768572 0.91 ALDH1A1 (0.34) ALDH1A1LMNASMN1; SMN2GSRKDM4E
Acetic Acid SCHEMBL11173531 0.91 PTGS2 (0.34) LMNASMN1; SMN2GSRKDM4EDUSP3
Nitroglycerin SCHEMBL1746747 0.89 PTGS2 (0.36) GSR
Nitric Acid SCHEMBL28312897 0.89 THRB (0.45)
Acetic Acid SCHEMBL27494476 0.86 PTGS2 (0.35) ALDH1A1LMNASMN1; SMN2GSRKDM4E
SCHEMBL2728056 0.84 ALDH1A1 (0.42) CA5ACA5BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6535 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
EP-4705284-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO Emory University (US) 2026-03-11 EP claimed
US-20260048181-A1 ANTIMICROBIAL POLYCARBONATE COATINGS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-02-19 US claimed
WO-2025235664-A1 PURINE NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2025-11-13 WO claimed
EP-4625575-A1 LITHIUM ION BATTERY AND ELECTRIC DEVICE BYD Company Limited (CN) 2025-10-01 EP claimed
US-20250288607-A1 METHODS FOR TREATING SEXUAL DYSFUNCTION ASSOCIATED WITH POLYCYSTIC OVARY SYNDROME (PCOS) OR WITH HYPOACTIVE SEXUAL DESIRE DISORDER (HSDD) Institut National de la Santé et de la Recherche Médicale (FR) 2025-09-18 US claimed
US-20250288555-A1 SYSTEMS AND METHODS TO IMPROVE EXERCISE TOLERANCE EPICENTRX, INC. (US) 2025-09-18 US claimed
US-20250248940-A1 Biopolymer Formulations for Drug Delivery 11584022 CANADA INC. (CA) 2025-08-07 US claimed
EP-4597676-A1 LITHIUM BATTERY AND ELECTRICAL DEVICE BYD Company Limited (CN) 2025-08-06 EP claimed
US-20250246609-A1 LITHIUM BATTERY AND ELECTRICAL DEVICE BYD COMPANY LIMITED (CN) 2025-07-31 US claimed
WO-1992004011-A1 DOSAGE FORM FOR TIME-VARYING PATTERNS OF DRUG DELIVERY ALZA CORPORATION (US) 1992-03-19 WO claimed
WO-1992000729-A1 DOSAGE FORM FOR ADMINISTERING A DRUG TO EFFECT CIRCADIAN THERAPY ALZA CORPORATION (US) 1992-01-23 WO claimed
US-4952402-A EDIBLE TASTE-MASKED DRUGS; MICROMATRIX ACTIVE MATERIAL COATED WITH NONTOXIC POLYMER; LIQUIDS; TABLETS ELAN CORPORATION, P.L.C. (IE) 1990-08-28 US claimed
EP-0284849-A1 Sustained release tablets on the basis of high molecular weight hydroxypropylmethylcellulose and a process for their manufacture LEK, tovarna farmacevtskih in kemicnih izdelkov, n.sol.o. (SI) 1988-10-05 EP claimed
EP-0251425-A1 Article for administration of pharmacologically-active substances HERCON LABORATORIES CORPORATION (US) 1988-01-07 EP claimed
US-4711887-A HYPOTENSIVE AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-12-08 US claimed
US-4369172-A Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose FOREST LABORATORIES INC. (US) 1983-01-18 US claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
US-4112115-A Therapy of leg muscle cramps COGHLAN CHARLES C 1978-09-05 US claimed
US-3957549-A PETRIN ACRYLATE, DINITROPROPYL ACRYLATE, ACRYLIC ACID THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-05-18 US claimed