Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422341 | 0.90 | NCEH1 (0.43) | MGLLALDH1A1HSD17B10 | |
| SCHEMBL4423636 | 0.89 | ALDH1A1 (0.47) | PLA2G2AMGLLACHENPC1RAB9A | |
| SCHEMBL3921491 | 0.87 | ALDH1A1 (0.47) | PLA2G2ANPC1RAB9AGABRG2GABRB3 | |
| SCHEMBL4429632 | 0.86 | ALDH1A1 (0.43) | PLA2G2AALDH1A1HSD17B10 | |
| SCHEMBL4417423 | 0.86 | MGLL (0.43) | PLA2G2AMGLLALDH1A1 | |
| SCHEMBL4424973 | 0.86 | MEN1 (0.46) | PLA2G2ANPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL4426908 | 0.86 | MEN1 (0.46) | PLA2G2ANPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL4422551 | 0.86 | PLA2G2A (0.44) | PLA2G2ANPC1RAB9ATDP1CNR2 | |
| SCHEMBL4428456 | 0.85 | MEN1 (0.46) | PLA2G2ANPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL4416088 | 0.84 | PLA2G2A (0.42) | PLA2G2ANPC1RAB9AGABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |