SCHEMBL12609477

SCHEMBL12609477

CC(=O)O/N=C1\CCCCc2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.63
MAPT P10636 9/20 0.63
L3MBTL1 Q9Y468 4/20 0.63
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
PLA2G1B P04054 1/20 0.63
ATG4B Q9Y4P1 1/20 0.63
ALDH1A1 P00352 7/20 0.60
CASP3 P42574 1/20 0.59
SENP8 Q96LD8 1/20 0.59
SENP7 Q9BQF6 1/20 0.59
SENP6 Q9GZR1 1/20 0.59
NPC1 O15118 1/20 0.59
PKM P14618 1/20 0.58
HPGD P15428 1/20 0.56
MAPK1 P28482 1/20 0.48
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GAA P10253 1/20 0.46
ALOX12 P18054 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5189232 0.97 LMNA (0.68) LMNAMAPTL3MBTL1KMT2AMEN1
SCHEMBL12609515 0.97 LMNA (0.68) LMNAMAPTL3MBTL1KMT2AMEN1
SCHEMBL4418793 0.90 LMNA (0.55) LMNAMAPTL3MBTL1KMT2AMEN1
SCHEMBL4418795 0.90 LMNA (0.55) LMNAMAPTL3MBTL1KMT2AMEN1
SCHEMBL12101822 0.90 LMNA (0.55) LMNAMAPTL3MBTL1KMT2AMEN1
SCHEMBL12609517 0.82 MAPT (0.76) LMNAMAPTL3MBTL1KMT2AMEN1
SCHEMBL17190976 0.78 L3MBTL1 (0.59) LMNAMAPTL3MBTL1KMT2AMEN1
SCHEMBL12609480 0.78 MAPT (0.55) LMNAMAPTL3MBTL1KMT2AMEN1
SCHEMBL2045185 0.77 MAPT (0.34) LMNAMAPTL3MBTL1KMT2AMEN1
SCHEMBL2045183 0.77 MAPT (0.34) LMNAMAPTL3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120282549-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, PHOTOSENSITIVE LAMINATE, METHOD FOR FORMING PERMANENT PATTERN, AND PRINTED BOARD FUJIFILM CORPORATION (JP) 2012-11-08 US disclosed
US-20120282549-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, PHOTOSENSITIVE LAMINATE, METHOD FOR FORMING PERMANENT PATTERN, AND PRINTED BOARD FUJIFILM CORPORATION (JP) 2012-11-08 US disclosed
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-20100015352-A1 INK-JET INK COMPOSITION, AND INK-JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed
US-20100015352-A1 INK-JET INK COMPOSITION, AND INK-JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS LMNA 3886/4885MAPT 3766/4885L3MBTL1 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.