Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407478 | 0.99 | ALPL (0.40) | ALPLALPICYP19A1MAPTALDH1A1 | |
| SCHEMBL4881596 | 0.89 | MAPT (0.42) | ALPLMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4878959 | 0.88 | ALPL (0.40) | ALPLALPICYP19A1MAPTALDH1A1 | |
| SCHEMBL4878918 | 0.86 | CHRM2 (0.53) | ALPLALPICYP19A1MAPTALDH1A1 | |
| SCHEMBL4001032 | 0.83 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL4057724 | 0.80 | LMNA (0.43) | CYP19A1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4878565 | 0.78 | MAPT (0.60) | MAPTALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL4002446 | 0.78 | CHRM2 (0.59) | MAPTALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL4655851 | 0.77 | LMNA (0.44) | ALDH1A1NPSR1CA9LMNAPKM | |
| SCHEMBL4881541 | 0.77 | MAPT (0.43) | ALPLMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016042-A1 | PROCESS FOR PREPARING TOLTERODINE OR ITS SALT AND SYNTHETIC INTERMEDIATE | Estechpharma Co. Ltd. (KR) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007126217-A1 | PROCESS FOR PREPARING TOLTERODINE OR ITS SALT AND SYNTHETIC INTERMEDIATE | ESTECHPHARMA CO., LTD. (KR) | 2007-11-08 | — | — | WO | disclosed |