Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1353022 | 0.92 | HTR7 (0.48) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12856665 | 0.92 | LMNA (0.40) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4001032 | 0.87 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL4881596 | 0.83 | MAPT (0.42) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23209991 | 0.82 | LMNA (0.48) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11259445 | 0.81 | AR (0.48) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23210311 | 0.81 | LMNA (0.44) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4002446 | 0.81 | CHRM2 (0.59) | LMNAMAPTALDH1A1HPGDCHRM2 | |
| SCHEMBL13219204 | 0.81 | SGMS2 (0.43) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL580390 | 0.80 | CHRM2 (0.40) | LMNAMAPTPTGER1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701932-B1 | TOLTERODINE, COMPOSITIONS AND USES THEREOF, AND PREPARATION OF THE SAME | CIPLA LTD (IN) | 2012-07-18 | — | — | EP | disclosed |
| US-20110282094-A1 | PROCESS FOR PREPARATION OF PHENOLIC MONOESTERS OF HYDROXYMETHYL PHENOLS | INTAS PHARMACEUTICALS LIMITED (IN) | 2011-11-17 | — | — | US | disclosed |
| US-7538249-B2 | Tolterodine, compositions and uses thereof, and preparation of the same | CIPLA LIMITED (IN) | 2009-05-26 | — | — | US | disclosed |
| US-20080146844-A1 | PROCESS FOR PREPARING TOLTERODINE | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-06-19 | — | — | US | disclosed |
| US-20080146844-A1 | PROCESS FOR PREPARING TOLTERODINE | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-06-19 | — | — | US | disclosed |
| US-7355077-B2 | Process for preparing tolterodine | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-04-08 | — | — | US | disclosed |
| US-7355077-B2 | Process for preparing tolterodine | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-04-08 | — | — | US | disclosed |
| US-20070142479-A1 | Tolterodine, compositions and uses thereof, and preparation of the same | CIPLA LIMITED (IN) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146844-A1 | PROCESS FOR PREPARING TOLTERODINE | ADRA2B, ADRB3, ADRB1 | LMNA 2404/4885MAPT 1943/4885CYP1A2 141/4885 |
| US-20110282094-A1 | PROCESS FOR PREPARATION OF PHENOLIC MONOESTERS OF HYDROXYMETHYL PHENOLS | HPD, COMT, PNMT | LMNA 2384/4885MAPT 1212/4885CYP1A2 33/4885 |
| US-20070142479-A1 | Tolterodine, compositions and uses thereof, and preparation of the same | ADRB3, ADRB2, ADRB1 | LMNA 2746/4885MAPT 506/4885CYP1A2 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.