Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 4/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619435 | 0.82 | GMNN (0.37) | L3MBTL3L3MBTL1CCR3HRH1KCNH2 | |
| SCHEMBL24359592 | 0.77 | MEN1 (0.48) | SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL8579161 | 0.77 | LMNA (0.49) | — | |
| SCHEMBL8579167 | 0.77 | LMNA (0.49) | — | |
| SCHEMBL8579169 | 0.77 | LMNA (0.49) | — | |
| SCHEMBL13496684 | 0.74 | SIGMAR1 (0.49) | L3MBTL3L3MBTL1HRH1KCNH2SLC6A3 | |
| SCHEMBL1475576 | 0.73 | CCR3 (0.65) | L3MBTL1CCR3GAA | |
| SCHEMBL22657897 | 0.72 | ACHE (0.48) | L3MBTL3L3MBTL1SLC6A4GAA | |
| SCHEMBL85389 | 0.71 | SLC6A9 (0.42) | L3MBTL3L3MBTL1HRH1KCNH2SLC6A3 | |
| SCHEMBL9022573 | 0.71 | SLC6A4 (0.58) | KCNH2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061780-A1 | DIARYL PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Neuromed Pharmaceuticals, Ltd. (CA) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008031227-A1 | DIARYL PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2008-03-20 | — | — | WO | disclosed |