Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.30 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418349 | 0.79 | ADORA2A (0.30) | — | |
| SCHEMBL4420032 | 0.79 | TERT (0.40) | DYRK1A | |
| SCHEMBL12219421 | 0.77 | CCR8 (0.50) | CCR8KMT2APARP1RECQLTDP1 | |
| SCHEMBL4426693 | 0.75 | TERT (0.40) | DYRK1A | |
| SCHEMBL4420517 | 0.74 | GPR84 (0.38) | AHR | |
| SCHEMBL5271973 | 0.72 | TDP1 (0.43) | CCR8KMT2APARP1RECQLTDP1 | |
| SCHEMBL12219425 | 0.71 | CCR8 (0.52) | CCR8KMT2APARP1DYRK1AAHR | |
| SCHEMBL15629849 | 0.70 | P2RX7 (0.37) | CCR8KMT2APARP1RECQLTDP1 | |
| SCHEMBL19683290 | 0.69 | PARP1 (0.44) | CCR8KMT2APARP1RECQLTDP1 | |
| SCHEMBL2936176 | 0.68 | CFB (0.41) | PARP1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | claimed |
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | claimed |
| EP-1720615-B1 | COSMETIC HAIR DYEING COMPOSITIONS CONTAINING THEM AND USE THEREOF | PROCTER & GAMBLE (US) | 2009-12-30 | — | — | EP | disclosed |
| US-7468080-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-12-23 | — | — | US | disclosed |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | WELLA OPERATIONS US, LLC | 2008-06-12 | — | — | US | disclosed |
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1720615-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005087187-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, KRTCAP2 | CCR8 4339/4885KMT2A 1797/4885PARP1 1932/4885 |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, CKMT1A; CKMT1B, KRTCAP2 | CCR8 4339/4885KMT2A 1797/4885PARP1 1932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.