Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29070001 | 0.80 | CA12 (0.55) | LMNACA12CA9CA1CA2 | |
| SCHEMBL1618178 | 0.79 | LMNA (0.73) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL2966811 | 0.79 | LMNA (0.73) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL30760453 | 0.78 | LMNA (0.51) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11710533 | 0.78 | MEN1 (0.56) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7937234 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2APRMT5WDR77ALDH1A1 | |
| SCHEMBL24793066 | 0.75 | MEN1 (0.47) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL16379309 | 0.75 | KMT2A (0.49) | LMNACA1CA2MEN1KMT2A | |
| SCHEMBL7650160 | 0.75 | HTT (0.66) | LMNACA12CA9CA1CA2 | |
| SCHEMBL30760522 | 0.75 | ALDH1A1 (0.68) | LMNAMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240051-A1 | New process for the production of oxabispidines | ASTRAZENECA AB (SE) | 2009-09-24 | — | — | US | disclosed |
| US-20090036675-A1 | New process for production of oxabispidines | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | US | disclosed |
| US-7439355-B2 | Process for the production of oxabispidines | ASTRAZENECA AB (SE) | 2008-10-21 | — | — | US | disclosed |
| EP-1900741-A1 | New process for the production of oxabispidines | AstraZeneca AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| US-6936712-B1 | Process for the production of oxabispidines | ASTRAZENECA AB (SE) | 2005-08-30 | — | — | US | disclosed |
| US-20050171100-A1 | Process for the production of oxabispidines | ASTRAZENECA AB (SE) | 2005-08-04 | — | — | US | disclosed |
| EP-1330462-A1 | NEW PROCESS FOR THE PRODUCTION OF OXABISPIDINES | AstraZeneca AB (SE) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002028864-A1 | NEW PROCESS FOR THE PRODUCTION OF OXABISPIDINES | ASTRAZENECA AB (SE) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171100-A1 | Process for the production of oxabispidines | AVPR1B, CCNB3, CCNB1 | LMNA 3171/4885CA12 1275/4885CA9 1506/4885 |
| US-20090240051-A1 | New process for the production of oxabispidines | AVPR1B, CCNB1, QDPR | LMNA 3851/4885CA12 2085/4885CA9 2315/4885 |
| US-20090036675-A1 | New process for production of oxabispidines | AVPR1B, CCNB1, DHPS | LMNA 3919/4885CA12 2642/4885CA9 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.