Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18658904 | 0.85 | NR4A2 (0.59) | NR4A2ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL30155016 | 0.85 | NR4A2 (0.59) | NR4A2ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL437551 | 0.81 | NR4A2 (0.51) | NR4A2ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL440082 | 0.81 | LMNA (0.47) | ACHEBCHEGRIN1GRIN2APARP1 | |
| SCHEMBL22304342 | 0.81 | NR4A2 (0.51) | NR4A2ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL439645 | 0.81 | ACHE (0.46) | NR4A2ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL442137 | 0.81 | HTT (0.49) | ACHEBCHEGRIN1GRIN2ACYP1A2 | |
| SCHEMBL436602 | 0.78 | ACHE (0.44) | NR4A2ACHESOS2 | |
| SCHEMBL436589 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL439770 | 0.78 | BACE1 (0.42) | MAP4K4CYP1A2CYP2D6EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |