Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437952 | 0.85 | ACHE (0.45) | ACHEHTTBACE1PDPK1JAK2 | |
| SCHEMBL16224287 | 0.85 | BCHE (0.45) | BCHEACHEGRIN1GRIN2AHTT | |
| SCHEMBL442137 | 0.81 | HTT (0.49) | BCHEACHEGRIN1GRIN2AHTT | |
| SCHEMBL439853 | 0.81 | BCHE (0.43) | BCHEACHEGRIN1GRIN2ALMNA | |
| SCHEMBL442244 | 0.81 | ACHE (0.43) | BCHEACHEGRIN1GRIN2AHTT | |
| SCHEMBL437551 | 0.81 | NR4A2 (0.51) | BCHEACHEGRIN1GRIN2AGABRA1 | |
| SCHEMBL28317272 | 0.79 | HTT (0.43) | BCHEACHEGRIN1GRIN2AHTT | |
| SCHEMBL1557613 | 0.78 | TNF (0.42) | BCHEACHEGRIN1GRIN2AHTT | |
| SCHEMBL439366 | 0.78 | ALDH1A1 (0.46) | HTTLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL439635 | 0.78 | APP (0.48) | BCHEACHEGRIN1GRIN2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |