Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607616 | 0.83 | SMN1; SMN2 (0.50) | DPP4ATMEPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL7420932 | 0.76 | ALDH1A1 (0.42) | DPP4ATMEPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL7390148 | 0.73 | SMN1; SMN2 (0.61) | DPP4ATMEPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL7390156 | 0.73 | SMN1; SMN2 (0.61) | DPP4ATMEPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL22570787 | 0.72 | SMN1; SMN2 (0.50) | DPP4ATMEPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL21518541 | 0.72 | L3MBTL1 (0.43) | DPP4EPHX2SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL16822368 | 0.71 | KDM4E (0.41) | DPP4ATMEPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL211622 | 0.71 | KDM4E (0.44) | DPP4ATMEPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL11461186 | 0.71 | KDM4E (0.44) | DPP4ATMEPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL11457855 | 0.71 | KDM4E (0.44) | DPP4ATMEPHX1EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324386-B2 | Somatostatin-dopamine chimeric analogs | IPSEN PHARMA S.A.S. (FR) | 2012-12-04 | — | — | US | disclosed |
| US-8178651-B2 | Somatostatin-dopamine chimeric analogs | IPSEN PHARMA, S.A.S. (FR) | 2012-05-15 | — | — | US | disclosed |
| US-20100266704-A1 | OCTREOTIDE DEPOT FORMULATION WITH CONSTANTLY HIGH EXPOSURE LEVELS | NOVARTIS AG (CH) | 2010-10-21 | — | — | US | disclosed |
| US-20100179304-A1 | Somatostatin-Dopamine Chimeric analogs | IPSEN PHARMA S.A.S. (FR) | 2010-07-15 | — | — | US | disclosed |
| US-20090275501-A1 | Somatostatin-dopamine chimeric analogs | IPSEN PHARMA S.A.S. (FR) | 2009-11-05 | — | — | US | disclosed |
| US-7579435-B2 | Somatostatin-dopamine chimeric analogs | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2009-08-25 | — | — | US | disclosed |
| US-7572883-B2 | Somatostatin-dopamine chimeric analogs | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2009-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100266704-A1 | OCTREOTIDE DEPOT FORMULATION WITH CONSTANTLY HIGH EXPOSURE LEVELS | SSTR2, SSTR5, SSTR4 | DPP4 287/4885ATM 4752/4885EPHX1 4180/4885 |
| US-20100179304-A1 | Somatostatin-Dopamine Chimeric analogs | SSTR3, SLC6A3, PRLHR | DPP4 523/4885ATM 2712/4885EPHX1 3500/4885 |
| US-20090275501-A1 | Somatostatin-dopamine chimeric analogs | SSTR3, SLC6A3, PRLHR | DPP4 523/4885ATM 2712/4885EPHX1 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.