⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937547 | 0.78 | — | — | |
| SCHEMBL18568339 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL22791822 | 0.67 | — | — | |
| SCHEMBL1846174 | 0.65 | — | — | |
| SCHEMBL349091 | 0.65 | — | — | |
| SCHEMBL7701653 | 0.65 | GSK3A (0.32) | — | |
| SCHEMBL18007273 | 0.65 | — | — | |
| SCHEMBL11820953 | 0.65 | — | — | |
| SCHEMBL14870927 | 0.64 | FBP1 (0.38) | — | |
| SCHEMBL2227308 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108993555-A | A kind of preparation method of tardive dyskinesia rehabilitation pharmaceutical intermediate | 泰山医学院 | 2018-12-14 | — | — | CN | claimed |
| CN-106905335-A | Quinazo heterocycle compound and its preparation method and application | 北京工业大学 | 2017-06-30 | — | — | CN | claimed |
| WO-2025226831-A1 | PURINE COVALENT BASED CDK12 INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| CN-111344297-B | Cyclic dinucleotides as anticancer agents | 百时美施贵宝公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114787136-A | Substituted benzimidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-109422737-A | Imidazolone androgen receptor antagonists, preparation method and use | 上海时莱生物技术有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-108993555-A | A kind of preparation method of tardive dyskinesia rehabilitation pharmaceutical intermediate | 泰山医学院 | 2018-12-14 | — | — | CN | disclosed |
| CN-108993555-A | A kind of preparation method of tardive dyskinesia rehabilitation pharmaceutical intermediate | 泰山医学院 | 2018-12-14 | — | — | CN | disclosed |
| CN-107141309-A | Heteroaryl compound and its application method | 桑诺维恩药品公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-106905335-A | Quinazo heterocycle compound and its preparation method and application | 北京工业大学 | 2017-06-30 | — | — | CN | disclosed |
| WO-2017106426-A1 | FE NANOPARTICLES WITH PPM CONTENTS OF PD, CU AND/OR NI, REACTIONS IN WATER CATALYZED BY THEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-22 | — | — | WO | disclosed |
| WO-2008140197-A1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK HOLDINGS CO., LTD. (KR) | 2008-11-20 | — | — | WO | disclosed |
| CN-101243043-A | Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field | GIULIANI INT LTD (IE) | 2008-08-13 | — | — | CN | disclosed |
| CN-100341873-C | Pyrido 2,3-d pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2007-10-10 | — | — | CN | disclosed |
| CN-1768059-A | Pyrido 2,3-d pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2006-05-03 | — | — | CN | disclosed |
| CN-1711265-A | Novel amino-substituted dihydropyrimido[4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2005-12-21 | — | — | CN | disclosed |
| EP-1560831-A1 | NOVEL AMINO-SUBSTITUTED DIHYDROPYRIMIDO [4,5-D] PYRIMIDIN ONE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041823-A1 | NOVEL AMINO-SUBSTITUTED DIHYDROPYRIMIDO[4,5-D]PYRIMIDINONE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-21 | — | — | WO | disclosed |
| US-5610303-A | MONOAMIDE OXIDASE INHIBITORS | UBE INDUSTRIES, LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0059884-B1 | BENZOFURANE DERIVATIVES, THEIR PREPARATION AND USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-22 | — | — | EP | disclosed |