⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18568339 | 0.84 | ALDH1A1 (0.31) | — | |
| SCHEMBL4422198 | 0.78 | — | — | |
| SCHEMBL349091 | 0.76 | — | — | |
| SCHEMBL1846174 | 0.76 | — | — | |
| SCHEMBL12195354 | 0.73 | GPR35 (0.31) | — | |
| SCHEMBL11938776 | 0.69 | POLB (0.32) | — | |
| SCHEMBL378762 | 0.68 | — | — | |
| SCHEMBL11820953 | 0.67 | — | — | |
| SCHEMBL7701653 | 0.67 | GSK3A (0.32) | — | |
| SCHEMBL2227308 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025882-A1 | BENZAMIDES OF PYRAZOLYLAMINO- PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-01-25 | — | — | US | disclosed |
| WO-2019188499-A1 | METHOD FOR PRODUCING α-OLEFIN/(METH)ACRYLIC ACID ESTER COPOLYMER | 日本ポリエチレン株式会社 | 2019-10-03 | — | — | WO | disclosed |
| US-8841276-B2 | Fulvene and fulvalene analogs and their use in treating cancers | EMORY UNIVERSITY (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130338208-A1 | FULVENE AND FULVALENE ANALOGS AND THEIR USE IN TREATING CANCERS | U.S. GOVERNMANET AS REPRESENTED BY UNITED STATES DEPARTMENT OF VETERANS AFFAIRS (US) | 2013-12-19 | — | — | US | disclosed |
| WO-2013149185-A1 | PROCESSES FOR PREPARING TUBULYSIN DERIVATIVES AND CONJUGATES THEREOF | ENDOCYTE, INC. (US) | 2013-10-03 | — | — | WO | disclosed |
| CN-101772344-A | Fulvene and fulvalene analogs and their use in the treatment of cancer | UNIV EMORY (US) | 2010-07-07 | — | — | CN | disclosed |
| EP-2148666-A1 | FULVENE AND FULVALENE ANALOGS AND THEIR USE IN TREATING CANCERS | Emory University (US) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008137740-A1 | FULVENE AND FULVALENE ANALOGS AND THEIR USE IN TREATING CANCERS | EMORY UNIVERSITY (US) | 2008-11-13 | — | — | WO | disclosed |
| US-20080275016-A1 | For drug resistant cancers; antiinflammatory agents;degenerative or vascular diseases; blocking nitrogen oxide so growth of tumors is suppressed | U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, THE | 2008-11-06 | — | — | US | disclosed |