⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18568339 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL2937547 | 0.76 | — | — | |
| SCHEMBL12195354 | 0.70 | GPR35 (0.31) | — | |
| SCHEMBL17735456 | 0.67 | — | — | |
| SCHEMBL11938776 | 0.66 | POLB (0.32) | — | |
| SCHEMBL4422198 | 0.65 | — | — | |
| SCHEMBL378762 | 0.65 | — | — | |
| SCHEMBL11820953 | 0.64 | — | — | |
| SCHEMBL7701653 | 0.64 | GSK3A (0.32) | — | |
| SCHEMBL1846174 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206723-A1 | BIOLOGICAL INDICATOR | American Sterilizer Company (US) | 2017-08-23 | — | — | EP | claimed |
| WO-2016060714-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2016-04-21 | — | — | WO | claimed |
| EP-2718459-A2 | COMPETITION-BASED DETECTION ASSAYS | Shire Human Genetic Therapies, Inc. (US) | 2014-04-16 | — | — | EP | claimed |
| US-20140038181-A1 | CHEMICALLY SUBSTITUTED THERMOSENSITIVE PROBES AND COFACTORS FOR HOT START LIGATION | TRILINK BIOTECHNOLOGIES, INC. | 2014-02-06 | — | — | US | claimed |
| WO-2012170870-A2 | COMPETITION BASED-DETECTION ASSAYS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2012-12-13 | — | — | WO | claimed |
| WO-2012166848-A2 | METHODS AND COMPOSITIONS FOR THE DETECTION OF FUNCTIONAL CLOSTRIDIUM DIFFICILE TOXINS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-12-06 | — | — | WO | claimed |
| EP-2507629-A1 | ENZYMATIC ACTIVITY-BASED DETECTION | Shire Human Genetic Therapies (US) | 2012-10-10 | — | — | EP | claimed |
| WO-2012094343-A1 | CHEMICALLY SUBSTITUTED THERMOSENSITIVE PROBES AND COFACTORS FOR HOT START LIGATION | TRILINK BIOTECHNOLOGIES (US) | 2012-07-12 | — | — | WO | claimed |
| EP-1945208-A2 | COMPOSITION AND SYNTHESIS OF NEW REAGENTS FOR INHIBITION OF HIV REPLICATION | University of Massachusetts (US) | 2008-07-23 | — | — | EP | claimed |
| US-20070099919-A1 | Composition and synthesis of new reagents for inhibition of HIV replication | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-03 | — | — | US | claimed |
| WO-2007044565-A2 | COMPOSITION AND SYNTHESIS OF NEW REAGENTS FOR INHIBITION OF HIV REPLICATION | UNIVERSITY OF MASSACHUSETTS (US) | 2007-04-19 | — | — | WO | claimed |
| CN-1422262-A | 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors | ABBOTT GMBH & CO KG (DE) | 2003-06-04 | — | — | CN | claimed |
| EP-0233733-A2 | Process for producing N-phthaloyl-p-nitro-L-phenylalanine | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-08-26 | — | — | EP | claimed |
| US-20240140980-A1 | HETEROCYCLIC INHIBITORS OF CD73 FOR TREATMENT OF DISEASE | TEON THERAPEUTICS, INC. | 2024-05-02 | — | — | US | disclosed |
| WO-2024086663-A1 | ETHER LIPIDS FOR HYPERACTIVATION OF MAMMALIAN DENDRITIC CELLS | CORNER THERAPEUTICS, INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| WO-2024076873-A1 | HETEROCYCLIC INHIBITORS OF CD73 FOR TREATMENT OF DISEASE | TEON THERAPEUTICS, INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| EP-0002236-A1 | Peptides, their salts, their acid addition salts, pharmaceutical formulations containing them and their use as morphine antagonists and anaesthetics | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-06-13 | — | — | EP | disclosed |
| US-4055657-A | S-ARYL-N-ALKYL-THIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-4006137-A | ANTHELMINTIC | E. R. SQUIBB & SONS, INC. (US) | 1977-02-01 | — | — | US | disclosed |
| US-3978079-A | DIPHTHALIMIDO, DISUCCINIMIDO AND DIMALEIMIDO OXALATES | AMERICAN CYANAMID COMPANY (US) | 1976-08-31 | — | — | US | disclosed |