Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 9/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410673 | 0.83 | NOTUM (0.58) | NOTUMHTR7PRMT5WDR77HTR1A | |
| SCHEMBL29963849 | 0.81 | MEN1 (0.52) | NOTUML3MBTL1HTR7PRMT5WDR77 | |
| SCHEMBL5966716 | 0.81 | MEN1 (0.52) | NOTUML3MBTL1HTR7PRMT5WDR77 | |
| SCHEMBL578432 | 0.80 | NOTUM (0.50) | NOTUMHTR7PRMT5WDR77HTR1A | |
| SCHEMBL19410662 | 0.78 | NOTUM (0.53) | NOTUMHTR7PRMT5WDR77HTR1A | |
| SCHEMBL4064792 | 0.76 | AADAT (0.54) | L3MBTL1POLBPYGL | |
| SCHEMBL5966758 | 0.75 | CCKBR (0.48) | NOTUMMAPT | |
| SCHEMBL30382092 | 0.75 | HTR7 (0.53) | NOTUMHTR7PRMT5WDR77HTR1A | |
| SCHEMBL2954869 | 0.75 | HTR7 (0.53) | NOTUMHTR7PRMT5WDR77HTR1A | |
| SCHEMBL5113192 | 0.75 | HTR7 (0.53) | NOTUMHTR7PRMT5WDR77HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756071-B1 | BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA SA (BE) | 2009-08-26 | — | — | EP | claimed |