Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD5 | P21918 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382092 | 1.00 | HTR7 (0.53) | HTR7NOTUMHTR1AHPGDDRD2 | |
| Hydrochloric Acid SCHEMBL29877918 | 0.98 | HTR7 (0.51) | HTR7NOTUMHTR1AHPGDDRD2 | |
| SCHEMBL25162957 | 0.98 | HPGD (0.53) | HTR7NOTUMHTR1AHPGDDRD2 | |
| SCHEMBL5507788 | 0.86 | CES1 (0.53) | ALDH1A1 | |
| SCHEMBL8240109 | 0.85 | HTR7 (0.57) | HTR7NOTUMHTR1ADRD2DRD5 | |
| SCHEMBL9095440 | 0.84 | HDAC3 (0.44) | HTR7NOTUMHTR1ADRD2DRD5 | |
| SCHEMBL29525493 | 0.83 | POLB (0.65) | DRD2DRD3DRD4ATAD2 | |
| SCHEMBL8556193 | 0.83 | POLB (0.65) | DRD2DRD3DRD4ATAD2 | |
| SCHEMBL7476444 | 0.82 | DRD2 (0.63) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL5506721 | 0.82 | GAA (0.51) | HTR7HPGDBRD4ATAD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768781-A | Method for synthesizing quaternary carbon o-diamine by photocatalysis | 大连理工大学 | 2023-09-19 | — | — | CN | claimed |
| WO-2024059665-A1 | DIMERIC COMPOUNDS AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |
| US-11814367-B2 | Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof | MAZE THERAPEUTICS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| CN-116768781-A | Method for synthesizing quaternary carbon o-diamine by photocatalysis | 大连理工大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-111333660-B | 550nm excited rhodamine dye and preparation method thereof | 中国科学院大连化学物理研究所 | 2022-03-18 | — | — | CN | disclosed |
| CN-108658835-B | Method for synthesizing indole-2-ketone compound | 中国科学院成都有机化学有限公司 | 2021-12-03 | — | — | CN | disclosed |
| US-20210130371-A1 | PYRUVATE KINASE ACTIVATORS FOR USE IN TREATING BLOOD DISORDERS | AGIOS PHARMACEUTICALS, INC. | 2021-05-06 | — | — | US | disclosed |
| CN-112088157-A | Aryl-bipyridine amine derivatives as phosphoinositide kinase inhibitors | 拉文纳制药公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-111334079-A | Full-spectrum high-brightness and high-stability fluorescent dye and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | disclosed |
| US-4831031-A | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity | PFIZER INC. (US) | 1989-05-16 | — | — | US | disclosed |
| US-4810801-A | Pyrrolobenzimidazoles, pharmaceutical compositions containing them, and use of them to treat certain heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1989-03-07 | — | — | US | disclosed |
| EP-0281309-A1 | Piperazinyl-heterocyclic compounds | PFIZER INC. (US) | 1988-09-07 | — | — | EP | disclosed |
| US-4686224-A | Oxindole antiinflammatory agents | PFIZER INC. (US) | 1987-08-11 | — | — | US | disclosed |
| US-4644005-A | ANTIARTHRITIC AGENTS | PFIZER INC. (US) | 1987-02-17 | — | — | US | disclosed |
| EP-0181136-A2 | Oxindole antiinflammatory agents | PFIZER INC. (US) | 1986-05-14 | — | — | EP | disclosed |
| EP-0048834-A1 | Method for measurement of trace enzymes | FUJI PHOTO FILM CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |
| US-4160032-A | Oxindoles as sleep-inducers | SANDOZ, INC. (US) | 1979-07-03 | — | — | US | disclosed |
| US-4051099-A | ISOINDOLES | CIBA-GEIGY CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
| US-3961952-A | ELECTROPHOTOGRAPHY, SUPPORTS, COATINGS | ITEK CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814367-B2 | Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof | GYS2, GYS1, PYGL | HTR7 4171/4885NOTUM 3025/4885HTR1A 2664/4885 |
| US-20210130371-A1 | PYRUVATE KINASE ACTIVATORS FOR USE IN TREATING BLOOD DISORDERS | PDK1, PDK2, PDK3 | HTR7 4074/4885NOTUM 3861/4885HTR1A 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.