SCHEMBL442274

SCHEMBL442274

COc1ccc(/C=C/C#N)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.57
CYP3A4 P08684 3/20 0.57
TSHR P16473 2/20 0.57
ALDH1A1 P00352 2/20 0.57
LMNA P02545 2/20 0.57
TP53 P04637 1/20 0.57
TRPA1 O75762 1/20 0.55
RELA Q04206 1/20 0.55
CYP1A2 P05177 4/20 0.53
CYP1A1 P04798 3/20 0.53
CYP1B1 Q16678 3/20 0.53
ESR1 P03372 2/20 0.53
PTGS2 P35354 2/20 0.53
AHR P35869 2/20 0.53
ABL1 P00519 1/20 0.53
TTR P02766 1/20 0.53
ABCB1 P08183 1/20 0.53
ALOX5 P09917 1/20 0.53
BCR P11274 1/20 0.53
CYP19A1 P11511 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442275 1.00 KDM4E (0.57) KDM4ECYP3A4TSHRALDH1A1LMNA
Acrylonitrile SCHEMBL3692651 0.93 KDM4E (0.50) KDM4ECYP3A4TSHRALDH1A1LMNA
Acrylonitrile SCHEMBL3692654 0.93 KDM4E (0.50) KDM4ECYP3A4TSHRALDH1A1LMNA
SCHEMBL2079488 0.89 KDM4E (0.59) KDM4ECYP3A4TSHRALDH1A1LMNA
SCHEMBL12845183 0.89 KDM4E (0.59) KDM4ECYP3A4TSHRALDH1A1LMNA
SCHEMBL22029554 0.85 FDPS (0.54) KDM4ECYP3A4TSHRALDH1A1LMNA
SCHEMBL12780456 0.84 RELA (0.57) KDM4ECYP3A4TSHRALDH1A1LMNA
SCHEMBL5149055 0.80 FDPS (0.49) KDM4ECYP3A4TSHRALDH1A1LMNA
SCHEMBL5149056 0.80 FDPS (0.49) KDM4ECYP3A4TSHRALDH1A1LMNA
SCHEMBL13790336 0.79 RELA (0.81) KDM4ECYP3A4TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708027-A Method for preparing boronated carbonyl derivative 中国科学院大连化学物理研究所 2025-03-28 CN claimed
EP-3240047-B1 PHOTOSENSITIVE COMPOSITION COMPRISING SEMICONDUCTOR NANOCRYSTALS AND METHOD FOR FORMING SEMICONDUCTOR NANOCRYSTAL PATTERN USING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2022-07-06 EP claimed
EP-3240047-A1 PHOTOSENSITIVE SEMICONDUCTOR NANOCRYSTALS, PHOTOSENSITIVE COMPOSITION COMPRISING SEMICONDUCTOR NANOCRYSTALS AND METHOD FOR FORMING SEMICONDUCTOR NANOCRYSTAL PATTERN USING THE SAME Samsung Electronics Co., Ltd. (KR) 2017-11-01 EP claimed
EP-1526584-B1 Method of forming electroluminescent semiconducting nanocrystal patterned layer for an organic-inorganic hybrid electroluminescent devices, and organic-inorganic hybrid electroluminescent device using the same. SAMSUNG ELECTRONICS CO LTD (KR) 2017-06-14 EP claimed
US-9466827-B2 Secondary battery NEC CORPORATION (JP) 2016-10-11 US claimed
US-8911883-B2 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-12-16 US claimed
US-8758864-B2 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-06-24 US claimed
US-20130011635-A1 PHOTOSENSITIVE SEMICONDUCTOR NANOCRYSTALS, PHOTOSENSITIVE COMPOSITION COMPRISING SEMICONDUCTOR NANOCRYSTALS AND METHOD FOR FORMING SEMICONDUCTOR NANOCRYSTAL PATTERN USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-01-10 US claimed
EP-2459727-A2 BIOCATALYST FOR CATALYTIC HYDROAMINATION BASF SE (DE) 2012-06-06 EP claimed
US-20120123155-A1 BIOCATALYST FOR CATALYTIC HYDROAMINATION BASF SE (DE) 2012-05-17 US claimed
EP-2280075-A1 Biocatalyst for catalytic hydroamination BASF SE (DE) 2011-02-02 EP claimed
CN-1655057-B Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and uses thereof SAMSUNG ELECTRONICS CO LTD 2010-12-08 CN claimed
US-7476487-B2 Inorganic nanocrystals surface-coordinated with a compound containing a photosensitive carbon to carbon double bond functional group is used for photolithographic process to form a pattern; curable with a curing agents; photomasking; simple method; organic-inorganic hybrid electroluminescent devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-01-13 US claimed
US-20080290797-A1 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-11-27 US claimed
US-7199393-B2 Photolithographic process to form a pattern, using an inorganic nanocrystals surface-coordinated with a compound containing a photosensitive carbon to carbon double bond functional group; photomasking; simple method; organic-inorganic hybrid electroluminescent devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-04-03 US claimed
US-20060199039-A1 Inorganic nanocrystals surface-coordinated with a compound containing a photosensitive carbon to carbon double bond functional group is used for photolithographic process to form a pattern; curable with a curing agents; photomasking; simple method; organic-inorganic hybrid electroluminescent devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-09-07 US claimed
CN-1655057-A Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and uses thereof SAMSUNG ELECTRONICS CO LTD (KR) 2005-08-17 CN claimed
US-20050161666-A1 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-07-28 US claimed
EP-1526584-A2 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same Samsung Electronics Co., Ltd (KR) 2005-04-27 EP claimed
US-4880624-A GUAIACOL, TRIMETHOXYBENZENE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1989-11-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120123155-A1 BIOCATALYST FOR CATALYTIC HYDROAMINATION HDHD5, PAH, GRHPR KDM4E 2889/4885CYP3A4 793/4885TSHR 3727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.