Sugi Predict

Sugi Predict / Compounds / SCHEMBL4423252

SCHEMBL4423252

SCHEMBL4423252

CNCC1COC(C)(C)O1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 2/20 0.58
▸ ALDH1A1 P00352 2/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ NAMPT P43490 3/20 0.35
▸ CHRM2 P08172 3/20 0.34
▸ CHRM4 P08173 3/20 0.34
▸ CHRM5 P08912 3/20 0.34
▸ CHRM3 P20309 3/20 0.34
▸ TMEM97 Q5BJF2 2/20 0.33
▸ SIGMAR1 Q99720 2/20 0.33
▸ CHRM1 P11229 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ ALOX15 P16050 1/20 0.31
▸ MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12786547 1.00 CA2 (0.58) CA2ALDH1A1NPSR1NAMPTCHRM2
SCHEMBL12786551 1.00 CA2 (0.58) CA2ALDH1A1NPSR1NAMPTCHRM2
SCHEMBL20689800 0.84 CA2 (0.59) CA2ALDH1A1NPSR1NAMPTCHRM2
SCHEMBL5990159 0.81 CA2 (0.56) CA2ALDH1A1NPSR1NAMPTCHRM2
SCHEMBL1760426 0.81 CA2 (0.61) CA2ALDH1A1NPSR1NAMPTCHRM2
SCHEMBL24465140 0.81 CA2 (0.56) CA2ALDH1A1NPSR1NAMPTCHRM2
SCHEMBL1760212 0.81 CA2 (0.61) CA2ALDH1A1NPSR1NAMPTCHRM2
SCHEMBL6844207 0.81 CA2 (0.56) CA2ALDH1A1NPSR1NAMPTCHRM2
SCHEMBL1760430 0.81 CA2 (0.61) CA2ALDH1A1NPSR1NAMPTCHRM2
SCHEMBL3500787 0.81 CA2 (0.56) CA2ALDH1A1NPSR1NAMPTCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023098752-A1 NOVEL NON-FLUORINATED QUINOLONE COMPOUND AND APPLICATION THEREOF 广州白云山医药集团股份有限公司白云山制药总厂 2023-06-08 — — WO disclosed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 — — US disclosed
EP-4006027-A1 PYRIDINE DERIVATIVE AS FGFR AND VEGFR DUAL INHIBITORS Medshine Discovery Inc. (CN) 2022-06-01 — — EP disclosed
EP-3985005-A1 FUSED RING COMPOUND AS FGFR AND VEGFR DUAL INHIBITOR Medshine Discovery Inc. (CN) 2022-04-20 — — EP disclosed
EP-3728237-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 — — EP disclosed
WO-2020249096-A1 FUSED RING COMPOUND AS FGFR AND VEGFR DUAL INHIBITOR 南京明德新药研发有限公司 2020-12-17 — — WO disclosed
US-20200315174-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2020-10-08 — — US disclosed
CN-110903275-A Process for producing iobitridol, intermediate therefor, and process for producing the same 苏州科伦药物研究有限公司 2020-03-24 — — CN disclosed
US-10308636-B2 Aromatic heterocyclic compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2019-06-04 — — US disclosed
WO-2019020466-A1 PROCESS FOR THE HYDROLYSIS OR ALCOHOLYSIS OF CYCLIC KETAL OR ACETAL GROUPS WITH CARBON DIOXIDE OR AN ALCOHOL BASF SE (DE) 2019-01-31 — — WO disclosed
US-6677483-B2 DISSOLVING DIETHYLENETRIAMINEPENTAACETIC- BISANHYDRIDE OF FORMULA IN DIMETHYL SULFOXIDE OR IN DIMETHYLFORMAMIDE OR IN A MIXTURE; ADDING SOLUBILIZER, AN AUXILIARY BASE AND A MONOAMINE OR DIAMINE, HEATING SCHERING AG (DE) 2004-01-13 — — US disclosed
EP-1353897-A1 METHOD FOR PRODUCING DTPA MONOAMIDES SCHERING AKTIENGESELLSCHAFT (DE) 2003-10-22 — — EP disclosed
US-20020155065-A1 Process for the production of monoamides of DTPA SCHERING AG (DE) 2002-10-24 — — US disclosed
WO-2002059076-A1 METHOD FOR PRODUCING DTPA MONOAMIDES SCHERING AKTIENGESELLSCHAFT (DE) 2002-08-01 — — WO disclosed
US-5387585-A Treating epilepsy, anxiety, sleep disorders, schizophrnia, senile dementia HOFFMANN-LA ROCHE INC. (US) 1995-02-07 — — US disclosed
EP-0519307-A2 Tetracyclic Imidazodiazepines F. HOFFMANN-LA ROCHE AG (CH) 1992-12-23 — — EP disclosed
US-4925652-A NUCLEAR MAGNETIC RESONANCE SCHERING AKTIENGESELLSCHAFT (DE) 1990-05-15 — — US disclosed
EP-0133674-B1 NITROXYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND DIAGNOSTIC AGENTS CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1989-09-20 — — EP disclosed
US-4845090-A NUCLEAR MAGNETIC RESONANCE SCHERING AKTIENGESELLSCHAFT (DE) 1989-07-04 — — US disclosed
EP-0133674-A1 Nitroxyl compounds, process for their preparation and diagnostic agents containing them SCHERING AKTIENGESELLSCHAFT (DE) 1985-03-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020155065-A1 Process for the production of monoamides of DTPA NAAA, PAM, DNPEP CA2 404/4885ALDH1A1 4498/4885NPSR1 480/4885
US-20200315174-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS UNG, TYMP, TYMS CA2 2425/4885ALDH1A1 170/4885NPSR1 3542/4885
US-10308636-B2 Aromatic heterocyclic compound GPR119, NR0B1, BET1 CA2 1729/4885ALDH1A1 887/4885NPSR1 829/4885
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS UNG, TYMP, TYMS CA2 2425/4885ALDH1A1 170/4885NPSR1 3542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.