SCHEMBL4423291

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4418956	0.89	PTGER1 (0.59)	SCD5SCDPTGER1ALDH1A1
	SCHEMBL2734042	0.89	PTGER1 (0.64)	SCD5SCDPTGER1ALDH1A1
	SCHEMBL2731497	0.89	PTGER1 (0.55)	SCD5SCDPTGER1ALDH1A1SMN1; SMN2
	SCHEMBL2733173	0.86	SCD5 (0.49)	SCD5SCDALDH1A1SMN1; SMN2KMT2A
	SCHEMBL4434304	0.86	SCD5 (0.52)	SCD5SCDALDH1A1SMN1; SMN2KMT2A
	SCHEMBL15190572	0.86	SCD5 (0.61)	SCD5SCDALDH1A1SMN1; SMN2MAPT
	SCHEMBL2732886	0.85	PTGER1 (0.59)	SCD5SCDPTGER1ALDH1A1SMN1; SMN2
	SCHEMBL4420874	0.85	SCD5 (0.55)	SCD5SCDALDH1A1SMN1; SMN2MAPT
	SCHEMBL4434159	0.84	SCD5 (0.50)	SCD5SCDALDH1A1SMN1; SMN2KMT2A
	SCHEMBL4429422	0.84	ALDH1A1 (0.54)	SCD5SCDALDH1A1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.