Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.51 |
| ▸ | RAF1 | P04049 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428564 | 0.82 | MAPK14 (0.44) | MAPK14RAF1TSHRMAPTHPGD | |
| SCHEMBL4420926 | 0.81 | MAPK14 (0.56) | MAPK14RAF1MEN1KMT2ATSHR | |
| SCHEMBL3220088 | 0.70 | MAPK14 (0.55) | MAPK14RAF1TSHRALDH1A1KDM4E | |
| SCHEMBL27605683 | 0.69 | MEN1 (0.50) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL6825878 | 0.69 | MEN1 (0.50) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL3241448 | 0.68 | MAPK14 (1.00) | MAPK14RAF1MEN1KMT2AALDH1A1 | |
| SCHEMBL13487957 | 0.67 | MAPK14 (0.52) | MAPK14RAF1MEN1KMT2AALDH1A1 | |
| SCHEMBL3539674 | 0.67 | MAPK14 (0.52) | MAPK14RAF1KMT2ATSHRALDH1A1 | |
| SCHEMBL7812401 | 0.66 | MAPK14 (0.48) | MAPK14RAF1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL28844152 | 0.65 | TRPM8 (0.56) | MEN1KMT2ATSHRKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4344960-B2 | — | — | 2009-10-14 | — | — | JP | claimed |
| JP-2001526687-A | — | — | 2001-12-18 | — | — | JP | claimed |
| EP-1019040-A4 | INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS | BAYER AG (US) | 2000-10-04 | — | — | EP | claimed |
| EP-1019040-A1 | INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS | Bayer Corporation (US) | 2000-07-19 | — | — | EP | claimed |
| WO-1998052558-A1 | INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS | BAYER CORPORATION (US) | 1998-11-26 | — | — | WO | claimed |