SCHEMBL4424231

SCHEMBL4424231

O=C(O)CNCCNS(=O)(=O)c1ncco1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 12/20 0.35
CA2 P00918 12/20 0.35
TBXA2R P21731 2/20 0.33
TBXAS1 P24557 1/20 0.33
ALDH1A1 P00352 2/20 0.33
LTA4H P09960 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4418224 0.78 CA1 (0.36) CA1CA2TBXA2RALDH1A1LMNA
SCHEMBL5561222 0.71 TSHR (0.39) CA1CA2ALDH1A1LMNA
SCHEMBL27657717 0.71 LTA4H (0.33) CA1CA2LTA4H
SCHEMBL3134597 0.70 ALDH1A1 (0.47) CA1CA2TBXA2RALDH1A1LMNA
SCHEMBL20024590 0.67 NR4A2 (0.43) LTA4H
SCHEMBL4413992 0.66 CA1 (0.41) CA1CA2
SCHEMBL26009424 0.63 CA1 (0.39) CA1CA2
SCHEMBL10988936 0.63 LMNA (0.44) CA1CA2LMNA
SCHEMBL163217 0.63 LMNA (0.44) CA1CA2LMNA
SCHEMBL11613680 0.63 EPHX2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651642-B1 PNA MONOMER AND PRECURSOR PANAGENE INC (KR) 2009-11-04 EP disclosed
US-7211668-B2 PNA monomer and precursor PANAGENE, INC. (KR) 2007-05-01 US disclosed
EP-1651642-A4 PNA MONOMER AND PRECURSOR PANAGENE INC (KR) 2006-11-29 EP disclosed
EP-1651642-A1 PNA MONOMER AND PRECURSOR Panagene Inc. (KR) 2006-05-03 EP disclosed
US-20050026930-A1 PNA monomer and precursor PANAGENE, INC. (KR) 2005-02-03 US disclosed
WO-2005009998-A1 PNA MONOMER AND PRECURSOR PANAGENE INC. (US) 2005-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026930-A1 PNA monomer and precursor RNGTT, POLL, NSUN3 CA1 1963/4885CA2 3196/4885TBXA2R 2316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.